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Predicted Role of NAD Utilization in the Control of Circadian Rhythms during DNA Damage Response

Fig 7

The effect of SIRT1 inhibition on non-histone components on CRY/PER mRNA levels.

Red: Simulation using parameter values from Table 2. Blue: Simulation using parameter values from Table 2 with a 25% decrease in VSIRT1c value.

doi: https://doi.org/10.1371/journal.pcbi.1004144.g007