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Robustness and Evolvability of the Human Signaling Network

Figure 6

A conceptual framework of the evolvable core and robust neighbor in biomolecular regulatory networks.

This figure shows that deletion of an evolvable core link causes acquiring a new phenotype, whereas deletion of a robust neighbor link causes cryptic genetic variation for the biological system represented by the attractor landscape.

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1003763.g006