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Nucleosome Free Regions in Yeast Promoters Result from Competitive Binding of Transcription Factors That Interact with Chromatin Modifiers

Figure 5

Predicted and observed nucleosome profiles around 5′ and 3′ ends of genes.

A: Averaged nucleosome coverage near transcription starts. Each curve shows the average nucleosome coverage at different positions relative to transcription start averaged over all genes. Red dashed lines correspond to experimentally measured nucleosome coverage (data from [1], right vertical axis). The solid lines correspond to the predicted nucleosome coverage by the model including only nucleosomes (light green) and the model including all TFs (blue), left vertical axis. B: Averaged nucleosome coverage near transcription ends. Curves are as described for panel A.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1003181.g005