Reconstruction and Validation of a Genome-Scale Metabolic Model for the Filamentous Fungus Neurospora crassa Using FARM
Figure 3
Metabolic overview of Neurospora crassa.
The 257 metabolic pathways of Neurospora are divided into the 35 color-coded pathway classes. Biosynthetic pathways are displayed on the left, energy metabolism in the center, and degradation pathways are on the right. In addition to the cytosol and extracellular space, the model also contains 4 organelles: these are the vacuole, the nucleus, and the mitochondrion. The 299 transport reactions enable uptake and excretion of 137 metabolites and also exchange between the cytosol and each organelle.