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Stochastic Simulations Suggest that HIV-1 Survives Close to Its Error Threshold

Figure 2

Structure of the quasispecies and the error threshold.

The structure of the quasispecies at different values of indicated (substitutions/site/replication) with (A) and (B) nucleotides. Inset in (B) compares the quasispecies structure predicted by our simulations for substitutions/site/replication (line) with that expected when all genomes occur with equal likelihood (i.e., ; see text) (symbols). (C) The mean Shannon entropy, , corresponding to the quasispecies in (A) and (B). Other parameters are the same as in Fig. 1.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1002684.g002