Skip to main content
Advertisement

< Back to Article

OptCom: A Multi-Level Optimization Framework for the Metabolic Modeling and Analysis of Microbial Communities

Figure 5

Comparison of the predicted fluxes by OptCom with estimates in the proposed model of [47].

The total predicted acetate and CO2 production rates by OptCom are in good agreement with experimental measurements by Miller et al [47]. Note that it was not possible to determine experimentally how much of the total acetate or CO2 available in the supernatant of the bioreactor is produced by which microorganism (the values provided by Miller et al [47] for the acetate and CO2 production by each species as well as all inter-organism flow rates are estimates and not experimental measurements). The values associated with the biomass of each microorganism represent fluxes (1/h) for OptCom predictions and concentrations (M) for experimental measurements [47].

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1002363.g005