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Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia

Figure 4

The state transition graph of the 6-node sub-network represented in Figure 2B.

It contains 64 states of which the state shown with a dark blue symbol is the normal fixed point and the state shown in red is the T-LGL fixed point. States denoted by light blue symbols are uniquely in the basin of attraction of the normal fixed point whereas the states in pink can only reach the T-LGL fixed point. Gray states, on the other hand, can lead to either fixed point.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1002267.g004