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Cellularly-Driven Differences in Network Synchronization Propensity Are Differentially Modulated by Firing Frequency
Figure 10
Differential effects of frequency modulation upon synchronization in stochastically-driven cortical pyramidal cell networks.
(A,B) Differences in bursting parameter B between high- and low-frequency networks as a function of synaptic weight 
and the re-wiring parameter for (A) Type I and (B) Type II networks. For Type I networks, 
and 
corresponded to high- and low-frequency networks, respectively, while for Type II networks, 
and 
corresponded to high- and low-frequency networks, respectively. (C,D) Values of the bursting parameter as a function of the re-wiring parameter for four different values of 
, with synaptic coupling fixed at 
in (C) and 
in (D). The circled regions in plots (A) and (B) were constructed by taking the difference between the highest- and lowest-frequency data points in (C) and (D). (E,F) Differences in MPC between high- and low-frequency networks as a function of synaptic weight and the re-wiring parameter for Type I and Type II networks. (G,H) Values of the MPC for four different values of 
, with synaptic coupling fixed at 
in (G) and 
in (H). The circled regions in plots (E) and (F) were constructed by taking the difference between the highest- and lowest-frequency data points in (G) and (H). Line colors in plots (G) and (H) correspond to the same legend as in plots (C) and (D), respectively.
doi: https://doi.org/10.1371/journal.pcbi.1002062.g010