Unraveling Protein Networks with Power Graph Analysis
Figure 1
The Three Basic Motifs: Star, Biclique, and Clique.
Stars often occur because of hub proteins or when affinity purification complexes are interpreted using the spoke model. Bicliques often arise because of domain-domain or domain-motif interactions inducing protein interactions [25]. Power nodes are sets of nodes and power edges connect power nodes. A power edge between two power nodes signifies that all nodes of the first set are connected to all nodes of the second set. Note that nodes within a power node are not necessarily connected to each other.