Signal Propagation in Proteins and Relation to Equilibrium Fluctuations
Figure 6
Importance of Secondary Structure in Defining Effective Means of Communication
Probability distribution of hitting times H(j,i) for the cases where residue j is located on (A) α-helices, (B) β-strands, and (C) loops or disordered regions. A total set of 49,929, 64,732, and 79,444 pairs contribute to the three respective curves, derived from the examined five enzymes. The abscissa represents the hitting time divided by the number of residues, which permits a normalization of the data collected for different proteins. The histograms are based on bins of size 0.2 in the interval [0, 10].