N-WASP Is Essential for the Negative Regulation of B Cell Receptor Signaling
Figure 4
The serum levels of anti-nuclear and anti-dsDNA antibody are elevated in cNKO mice.
(A) Representative images from immunofluorescence microscopic analysis of anti-nuclear antibody in the serum of littermate control and cNKO mice at 6 mo old (n = 4). (B) ELISA quantification of anti-dsDNA antibody in the serum of littermate control and cNKO mice at 6 and 9 mo old (n = 15). Each dot represents an individual mouse. *p<0.01.