Axonal Dynamics of Excitatory and Inhibitory Neurons in Somatosensory Cortex
Figure 6
Excitatory axons originating from neurons within non-deprived barrel columns.
(A) Excitatory axons located within non-deprived barrel columns. Left, axons located in rows A and B before whisker plucking. Right, same area following 1 mo of whisker plucking. (B–D) Axonal density in non-deprived cortex after 14 (B), 30 (C), and 60 (D) d of whisker plucking. Left column, first imaging session. Right column, second imaging session after the indicated period of plucking. As in Figure 5, the axonal density at each pair of time points was averaged over a set of mice and normalized by dividing each bin by the maximum region of local density in the baseline condition. Normalized mean axonal density is plotted (in arbitrary units) in 50 µm×50 µm bins with the respect to the injection site (asterisk) at coordinate (0,0,0). Distances are expressed in µm from injection site. Average location of barrel column for animals in each condition is indicated on each graph. Green labels refer to non-deprived barrel columns.