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Determination of Antioxidants and Preservatives in Cosmetics by SPME Combined with GC–MS

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Abstract

A rapid and simple procedure for the determination of antioxidants and preservatives in cosmetics has been developed utilizing solid-phase microextraction combined with GC–MS. A silica fiber coated with polyacrylate provided the highest extraction efficiency. Detection limits in the range from 0.4 to 8.5 ng mL−1 were obtained. Linearity is over a wide range from 1 to 2,000 ng mL−1 with a relative standard deviation under 16%. Cosmetic from a local supermarket were analysed for antioxidants and preservatives to demonstrate the effectiveness of the proposed method. The concentration of antioxidants and preservatives determined was 20–1,218 μg g−1 for methylparaben and 5–3,779 μg g−1 for propylparaben.

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Acknowledgments

The authors would like to thank the National Science Council of Taiwan for financially supporting this research under contract No. NSC 91-2113-M-005-025.

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Authors and Affiliations

  1. Department of Chemistry, National Chung Hsing University, Taichung, 40227, Taiwan

    Tzu-Feng Tsai & Maw-Rong Lee

  2. Department of Cosmetic Science, Providence University, Taichung, 40332, Taiwan

    Tzu-Feng Tsai

Authors
  1. Tzu-Feng Tsai
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  2. Maw-Rong Lee
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Correspondence to Maw-Rong Lee.

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Tsai, TF., Lee, MR. Determination of Antioxidants and Preservatives in Cosmetics by SPME Combined with GC–MS. Chroma 67, 425–431 (2008). https://doi.org/10.1365/s10337-007-0514-1

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  • DOI: https://doi.org/10.1365/s10337-007-0514-1

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