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Publicly Available Published by De Gruyter January 1, 2009

Novel pyrrole-containing hypoglycemic and hypotriglyceridemic compounds

  • Braj B. Lohray and Vidya Lohray
From the journal Pure and Applied Chemistry
https://doi.org/10.1351/pac200577010179
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Abstract

Several substituted α-alkoxy phenyl propionic acids were synthesized, and their hypotriglyceridemic properties were evaluated in Swiss albino mice. Some of the compounds showed excellent triglyceride- and cholesterol-lowering properties even at a dose of 1 mg/kg. 2,5-Substituted pyrrole-containing heterocycles were among the most potent alkoxy propionic acid class of compounds. These compounds also showed excellent antidiabetic activities in animal models.

Keywords: bioactive molecules; medicinal plants; pharmacology; phytochemistry

Conference

International Symposium on the Chemistry of Natural Products and the 4th International Congress on Biodiversity, International Conference on Biodiversity, International Symposium on the Chemistry of Natural Products, ICOB, ISCNP, Biodiversity, Natural Products, 24th, Delhi, India, 2004-01-26–2004-01-31

Published Online: 2009-01-01
Published in Print: 2005-01-01

© 2013 Walter de Gruyter GmbH, Berlin/Boston

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From the journal
Pure and Applied Chemistry
Pure and Applied Chemistry
Volume 77 Issue 1
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Journal and Issue

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