Archive BacDiveID:10.13145/bacdive1695.20221219.7.1

Strain identifier

BacDive ID: 1695

Type strain:

Species: Bifidobacterium breve

Strain Designation: S1

Strain history: CIP <- 1964, Lab. Ident. Inst. Pasteur, Paris, France <- M. Sebald, Inst. Pasteur, Paris, France <- H. Werner <- G. Reuter: strain S1

NCBI tax ID(s): 518634 (strain), 1685 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.

General

@ref: 8482

BacDive-ID: 1695

DSM-Number: 20213

keywords: genome sequence, 16S sequence, Bacteria, anaerobe, mesophilic, human pathogen

description: Bifidobacterium breve S1 is an anaerobe, mesophilic human pathogen that was isolated from intestine of infant.

NCBI tax id

NCBI tax id	Matching level
518634	strain
1685	species

strain history

<- G. Reuter, S1

ATCC 15700 <-- G. Reuter S1 (Variant a).

doi: 10.13145/bacdive1695.20221219.7.1

Name and taxonomic classification

LPSN

@ref: 20215
description: domain/bacteria
keyword: phylum/actinomycetota
domain: Bacteria
phylum: Actinomycetota
class: Actinomycetes
order: Bifidobacteriales
family: Bifidobacteriaceae
genus: Bifidobacterium
species: Bifidobacterium breve
full scientific name: Bifidobacterium breve Reuter 1963 (Approved Lists 1980)

@ref: 8482

domain: Bacteria

phylum: Actinobacteria

class: Actinobacteria

order: Bifidobacteriales

family: Bifidobacteriaceae

genus: Bifidobacterium

species: Bifidobacterium breve

full scientific name: Bifidobacterium breve Reuter 1963 emend. Nouioui et al. 2018

strain designation: S1

type strain: yes

Morphology

cell morphology

@ref: 69480
gram stain: positive
confidence: 94.355

Culture and growth conditions

culture medium

@ref	name	growth	link	composition
8482	BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58)	yes	https://mediadive.dsmz.de/medium/58	Name: BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58) Composition: Glucose 10.0 g/l Casein peptone 10.0 g/l Bacto Soytone 5.0 g/l Meat extract 5.0 g/l Yeast extract 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l MnSO4 x H2O 0.05 g/l KH2PO4 0.04 g/l K2HPO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Tween 80 Resazurin Distilled water
42088	MEDIUM 20 - for Anaerobic bacteria	yes		Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)

culture temp

@ref	growth	type	temperature	range
8482	positive	growth	37	mesophilic
42088	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic

Physiology and metabolism

oxygen tolerance

@ref	oxygen tolerance	confidence
8482	anaerobe
69480	anaerobe	98.357

spore formation

@ref: 69480
spore formation: no
confidence: 98.61

halophily

@ref: 69480
halophily level: non-halophilic
confidence: 98.11

murein

@ref: 8482
murein short key: A11.01
type: A3alpha L-Lys-Gly

metabolite utilization

@ref	metabolite	utilization activity	kind of utilization tested	Chebi-ID
68371	Potassium 5-ketogluconate	-	builds acid from
68371	Potassium 2-ketogluconate	-	builds acid from
68371	gluconate	-	builds acid from	24265
68371	L-arabitol	-	builds acid from	18403
68371	D-arabitol	-	builds acid from	18333
68371	D-fucose	-	builds acid from	28847
68371	D-tagatose	-	builds acid from	16443
68371	D-lyxose	-	builds acid from	62318
68371	turanose	+	builds acid from	32528
68371	glycogen	+	builds acid from	28087
68371	raffinose	+	builds acid from	16634
68371	melezitose	-	builds acid from	6731
68371	inulin	-	builds acid from	15443
68371	trehalose	-	builds acid from	27082
68371	sucrose	+	builds acid from	17992
68371	melibiose	+	builds acid from	28053
68371	lactose	+	builds acid from	17716
68371	maltose	+	builds acid from	17306
68371	cellobiose	+	builds acid from	17057
68371	salicin	+	builds acid from	17814
68371	esculin	+	builds acid from	4853
68371	N-acetylglucosamine	+	builds acid from	59640
68371	methyl alpha-D-glucopyranoside	+	builds acid from	320061
68371	methyl alpha-D-mannoside	-	builds acid from	43943
68371	D-sorbitol	+	builds acid from	17924
68371	D-mannitol	+	builds acid from	16899
68371	myo-inositol	-	builds acid from	17268
68371	galactitol	-	builds acid from	16813
68371	L-rhamnose	-	builds acid from	62345
68371	L-sorbose	-	builds acid from	17266
68371	D-fructose	+	builds acid from	15824
68371	D-glucose	+	builds acid from	17634
68371	D-galactose	+	builds acid from	12936
68371	methyl beta-D-xylopyranoside	-	builds acid from	74863
68371	ribitol	-	builds acid from	15963
68371	L-xylose	-	builds acid from	65328
68371	D-xylose	-	builds acid from	65327
68371	D-ribose	+	builds acid from	16988
68371	L-arabinose	-	builds acid from	30849
68371	erythritol	-	builds acid from	17113
68371	glycerol	-	builds acid from	17754

API 50CHac

@ref	Q	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
8482	-	-	-	+	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	+	-	+	+	+	+	+	+	+	+	+	+	+	-	-	-	+	-	+	-	-	+	-	-	-	+	-	-	-	-	-
8482	-	-	-	-	-	+	-	-	-	-	+	+	+	-	-	-	-	-	+	+	-	+	+	+	+	+	+	+	+	+	+	+	-	-	-	+	-	+	-	-	+	-	-	-	+	-	-	-	-	-
8482	-	-	-	+	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	+	-	+	+	+	+	+	+	+	+	+	+	+	-	-	-	+	+/-	+	+/-	+	+	-	-	-	+	-	-	-	-	-
8482	-	-	-	+	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	+	-	+	+	+	+	+	+	+	+	+	+	+	-	-	-	+	+	+	+/-	+	+	-	-	-	+	-	-	-	-	-
8482	-	-	-	+	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	+	-	+	+	+	+	+	+	+	+	+	+	+	-	-	-	+	+	+	+	+	+	-	-	-	+	-	-	-	-	-
8482	-	-	-	-	-	+	-	-	-	-	+	+	+	+/-	-	-	-	-	+	+	-	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	-	+	-	-	+	-	-	-	+/-	-	-	-	-	-

Isolation, sampling and environmental information

isolation

@ref	sample type
8482	intestine of infant
67770	Intestine of infant

isolation source categories

Cat1	Cat2	Cat3
#Host	#Human	#Child
#Host Body-Site	#Gastrointestinal tract

taxonmaps

@ref: 69479
File name: preview.99_711.png
url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_24;96_219;97_238;98_571;99_711&stattab=map
Last taxonomy: Bifidobacterium breve subclade
16S sequence: LC071793
Sequence Identity:
Total samples: 147666
soil counts: 1133
aquatic counts: 3177
animal counts: 142996
plant counts: 360

Safety information

risk assessment

@ref: 8482
pathogenicity human: yes, in single cases
biosafety level: 1
biosafety level comment: Risk group (German classification)

Sequence information

16S sequences

@ref	description	accession	length	database	NCBI tax ID
20218	Bifidobacterium breve gene for 16S rRNA, partial sequence, strain: ATCC 15700	AB006658	1520	ena	518634
20218	Bifidobacterium breve partial 16S rRNA gene, type strain ATCC 15700T	AM411121	179	ena	518634
20218	Bifidobacterium breve 16S ribosomal RNA	M58731	1536	ena	1685
20218	Bifodibacterium breve (ATCC 15700) 16S ribosomal RNA gene, partial	M84776	642	ena	1685
20218	Bifidobacterium breve strain DSM 20213 16S ribosomal RNA gene, partial sequence	HQ012023	939	ena	518634
20218	Bifidobacterium breve gene for 16S rRNA, partial sequence, strain: JCM 1192	AB116288	479	ena	518634
20218	Bifidobacterium breve gene for 16S rRNA, partial sequence, strain: JCM 1192	AB507084	672	ena	518634
20218	Bifidobacterium breve strain KCTC 3220 16S ribosomal RNA gene, partial sequence	GU361815	1483	ena	1685
67770	Bifidobacterium breve gene for 16S ribosomal RNA, partial sequence, strain: JCM 1192	LC071793	1418	ena	518634

Genome sequences

@ref	description	accession	assembly level	database	NCBI tax ID
66792	Bifidobacterium breve NCTC11815	GCA_900637145	complete	ncbi	1685
66792	Bifidobacterium breve DSM 20213 = JCM 1192 JCM 1192	GCA_001025175	complete	ncbi	518634
66792	Bifidobacterium breve DSM 20213 = JCM 1192	518634.7	wgs	patric	518634
66792	Bifidobacterium breve DSM 20213 = JCM 1192	518634.21	wgs	patric	518634
66792	Bifidobacterium breve DSM 20213 = JCM 1192	518634.20	complete	patric	518634
66792	Bifidobacterium breve DSM 20213 = JCM 1192	518634.19	wgs	patric	518634
66792	Bifidobacterium breve strain NCTC11815	1685.200	complete	patric	1685
66792	Bifidobacterium breve DSM 20213, JCM 1192	643886102	draft	img	518634
66792	Bifidobacterium breve DSM 20213, JCM 1192	2728369679	draft	img	518634
66792	Bifidobacterium breve DSM 20213	2667527587	draft	img	518634
66792	Bifidobacterium breve DSM 20213	2859463870	complete	img	518634
67770	Bifidobacterium breve DSM 20213 = JCM 1192 DSM 20213	GCA_000158015	scaffold	ncbi	518634
67770	Bifidobacterium breve DSM 20213 = JCM 1192 DNA, complete genome	AP012324		ena	518634
67770	Bifidobacterium breve DSM 20213 = JCM 1192 JCM 1192	GCA_001311295	contig	ncbi	518634
67770	Bifidobacterium breve DSM 20213 = JCM 1192 DSM 20213	GCA_000771305	contig	ncbi	518634
67770	Bifidobacterium breve strain NCTC11815 genome assembly, chromosome: 1	LR134348		ena	1685
66792	SAR324 cluster bacterium HCM1	GCA_002995645	scaffold	patric	2024889
66792	bacterium AalE_18-Q3-R2-46_BAT3C.1_cln	GCA_016699045	complete	patric	1869227
66792	Elusimicrobia bacterium Aved_18-Q3-R54-62_MAXAC.321	GCA_016702405	contig	patric	2030800
66792	Thiotrichales bacterium ZodW_maxbin.150	GCA_016938655	contig	patric	2026796
66792	Victivallales bacterium Tobar15.5-16.5m-G40	GCA_021733985	contig	patric	2212475

GC content

@ref	GC-content	method
8482	58.4
67770	58.4	thermal denaturation, midpoint method (Tm)

External links

@ref: 8482

culture collection no.: DSM 20213, ATCC 15700, NCTC 11815, JCM 1192, BCRC 11846, CCUG 18365, CCUG 30511, CECT 4839, CGMCC 1.2213, CIP 64.69, KCTC 3220, LMG 10501, LMG 11042, NCFB 2257

straininfo link

@ref	passport
20218	http://www.straininfo.net/strains/5433
20218	http://www.straininfo.net/strains/5426
20218	http://www.straininfo.net/strains/5438

literature

topic	Pubmed-ID	title	authors	journal	DOI	year	mesh	topic2
Pathogenicity	8872711	Growth characteristics of bifidobacteria in infant formulas.	Dubey UK, Mistry VV	J Dairy Sci	10.3168/jds.S0022-0302(96)76468-8	1996	Acetic Acid/metabolism, Animals, Bifidobacterium/cytology/growth & development, Buffers, Caseins, Fats/analysis, Humans, Hydrogen-Ion Concentration, Infant Food/analysis/microbiology, Infant, Newborn, Kinetics, Lactic Acid/biosynthesis, Milk, Protein Hydrolysates, Proteins/analysis, Soybeans	Enzymology
Pathogenicity	8872712	Effect of bifidogenic factors on growth characteristics of bifidobacteria in infant formulas.	Dubey UK, Mistry VV	J Dairy Sci	10.3168/jds.S0022-0302(96)76469-X	1996	Acetic Acid/metabolism, Bifidobacterium/drug effects/growth & development, Caseins, Colony Count, Microbial, Fructose/pharmacology, Humans, Hydrogen-Ion Concentration, Infant, Infant Food/analysis/microbiology, Lactic Acid/biosynthesis, Lactulose/pharmacology, Oligosaccharides/pharmacology, Protein Hydrolysates, Soybeans	Metabolism
Metabolism	9003583	Involvement of trihydroxyconjugated bile salts in cholesterol assimilation by bifidobacteria.	Tahri K, Grill JP, Schneider F	Curr Microbiol	10.1007/s002849900148	1997	Animals, Bifidobacterium/growth & development/metabolism, Bile/metabolism, Cattle, Cholagogues and Choleretics/pharmacology, Cholesterol/analysis/metabolism/pharmacology, Cholic Acid, Cholic Acids/pharmacology, Kinetics, Taurocholic Acid/pharmacology	Enzymology
Cultivation	10849172	Effects of fructooligosaccharides and their monomeric components on bile salt resistance in three species of bifidobacteria.	Perrin S, Grill JP, Schneider F	J Appl Microbiol	10.1046/j.1365-2672.2000.01070.x	2000	Animals, Bifidobacterium/drug effects/enzymology/growth & development, Bile Acids and Salts/pharmacology, Cattle, Culture Media, Drug Resistance, Microbial, Fructose/pharmacology, Glucose/pharmacology, Glycodeoxycholic Acid/pharmacology, Glycoside Hydrolases/metabolism, Oligosaccharides/*pharmacology, beta-Fructofuranosidase	Enzymology
Metabolism	11510661	The effect of nisin on the physiology of Bifidobacterium thermophilum.	Kot E, Murad Y, Bezkorovainy A	J Food Prot	10.4315/0362-028x-64.8.1206	2001	Anti-Bacterial Agents/pharmacology, Bifidobacterium/drug effects/growth & development/physiology, Ferric Compounds/metabolism, Lactic Acid/metabolism, Nisin/pharmacology, Time Factors	Physiology
Metabolism	12904543	Cholic acid accumulation and its diminution by short-chain fatty acids in bifidobacteria.	Kurdi P, Tanaka H, van Veen HW, Asano K, Tomita F, Yokota A	Microbiology (Reading)	10.1099/mic.0.26376-0	2003	Acetic Acid/pharmacology, Bifidobacterium/drug effects/metabolism, Bile Acids and Salts/metabolism, Biological Transport, Active/drug effects, Butyric Acid/pharmacology, Cholic Acid/metabolism, Energy Metabolism, Fatty Acids, Volatile/metabolism/*pharmacology, Humans, Hydrogen-Ion Concentration, Kinetics, Propionates/pharmacology	Pathogenicity
Metabolism	15222478	Growth-promoting effects of lactoferrin on L. acidophilus and Bifidobacterium spp.	Kim WS, Ohashi M, Tanaka T, Kumura H, Kim GY, Kwon IK, Goh JS, Shimazaki K	Biometals	10.1023/b:biom.0000027705.57430.f1	2004	Animals, Bifidobacterium/growth & development/metabolism, Cattle, Cell Fractionation, Cell Membrane/chemistry, Lactobacillus acidophilus/growth & development/metabolism, Lactoferrin/chemistry/*metabolism
Phylogeny	16391119	Modulation of rat cecal microbiota by administration of raffinose and encapsulated Bifidobacterium breve.	Dinoto A, Suksomcheep A, Ishizuka S, Kimura H, Hanada S, Kamagata Y, Asano K, Tomita F, Yokota A	Appl Environ Microbiol	10.1128/AEM.72.1.784-792.2006	2006	Administration, Oral, Animals, Bacteria/classification/genetics/isolation & purification, Bifidobacterium/genetics/growth & development/isolation & purification, Cecum/microbiology, Dietary Supplements, In Situ Hybridization, Fluorescence, Male, Oligonucleotide Probes, Polymorphism, Restriction Fragment Length, Raffinose/*administration & dosage, Rats	Enzymology
Pathogenicity	16484210	Mechanism of growth inhibition by free bile acids in lactobacilli and bifidobacteria.	Kurdi P, Kawanishi K, Mizutani K, Yokota A	J Bacteriol	10.1128/JB.188.5.1979-1986.2006	2006	Bifidobacterium/drug effects/metabolism, Bile Acids and Salts/pharmacology, Cell Membrane/drug effects/metabolism, Chenodeoxycholic Acid/pharmacology, Cholic Acid/pharmacology, Deoxycholic Acid/pharmacology, Hydrogen-Ion Concentration, Lactobacillus/*drug effects/metabolism, Membrane Potentials, Microbial Sensitivity Tests	Metabolism
Pathogenicity	17434219	Yoghurt fermented by Lactobacillus delbrueckii subsp. bulgaricus H+ -ATPase-defective mutants exhibits enhanced viability of Bifidobacterium breve during storage.	Ongol MP, Sawatari Y, Ebina Y, Sone T, Tanaka M, Tomita F, Yokota A, Asano K	Int J Food Microbiol	10.1016/j.ijfoodmicro.2007.02.019	2007	Bifidobacterium/growth & development, Colony Count, Microbial, Fermentation, Food Handling/methods, Food Preservation/methods, Humans, Hydrogen-Ion Concentration, Lactobacillus delbrueckii/genetics/physiology, Mutation, Proton-Translocating ATPases/deficiency/genetics, Temperature, Time Factors, Yogurt/microbiology
Pathogenicity	17927741	Oral administration of Bifidobacterium longum prevents gut-derived Pseudomonas aeruginosa sepsis in mice.	Matsumoto T, Ishikawa H, Tateda K, Yaeshima T, Ishibashi N, Yamaguchi K	J Appl Microbiol	10.1111/j.1365-2672.2007.03593.x	2007	Administration, Oral, Animals, Antibiosis, Bacterial Adhesion, Bifidobacterium, Colony Count, Microbial, Gastroenteritis/immunology/microbiology/therapy, Gastrointestinal Tract/microbiology, Immunocompromised Host, Male, Mice, Mice, Inbred ICR, Probiotics/administration & dosage, Pseudomonas Infections/immunology/microbiology/therapy, Pseudomonas aeruginosa/growth & development, Sepsis/immunology/microbiology/therapy
Pathogenicity	18837471	Synbiotic promotion of epithelial proliferation by orally ingested encapsulated Bifidobacterium breve and raffinose in the small intestine of rats.	Ishizuka S, Iwama A, Dinoto A, Suksomcheep A, Maeta K, Kasai T, Hara H, Yokota A	Mol Nutr Food Res	10.1002/mnfr.200800041	2009	Animals, Bifidobacterium/physiology, Bromodeoxyuridine/analysis, Cecum/chemistry/cytology/microbiology, Cell Division/drug effects, Colon/cytology, Epithelial Cells/cytology, Hydrogen-Ion Concentration, Intestine, Small/cytology, Male, Probiotics/administration & dosage, Raffinose/administration & dosage, Rats
Metabolism	19694435	In vitro fermentation of arabinoxylan-derived carbohydrates by bifidobacteria and mixed fecal microbiota.	Pastell H, Westermann P, Meyer AS, Tuomainen P, Tenkanen M	J Agric Food Chem	10.1021/jf901397b	2009	Arabinose/metabolism, Bifidobacterium/genetics/growth & development/metabolism, DNA, Bacterial/analysis, Feces/microbiology, Fermentation, Humans, Hydrogen-Ion Concentration, Oligosaccharides/metabolism, Species Specificity, Xylans/*metabolism, Xylose/metabolism	Pathogenicity
Pathogenicity	20583474	The influence of some probiotic supernatants on the growth and virulence features expression of several selected enteroaggregative E. coli clinical strains.	Lazar V, Miyazaki Y, Hanawa T, Chifiriuc MC, Ditu LM, Marutescu L, Bleotu C, Kamiya S	Roum Arch Microbiol Immunol		2009	Bacterial Adhesion, Bifidobacterium/growth & development, Cell Line, Colony Count, Microbial, Culture Media, Conditioned/chemistry/pharmacology, Diarrhea/microbiology, Enterococcus faecium/growth & development, Epithelial Cells/microbiology, Escherichia coli/drug effects/growth & development/pathogenicity, Escherichia coli Infections/microbiology, Humans, Lactobacillus casei/growth & development, Probiotics, Virulence	Cultivation
Metabolism	21832085	Physiology of consumption of human milk oligosaccharides by infant gut-associated bifidobacteria.	Asakuma S, Hatakeyama E, Urashima T, Yoshida E, Katayama T, Yamamoto K, Kumagai H, Ashida H, Hirose J, Kitaoka M	J Biol Chem	10.1074/jbc.M111.248138	2011	Adult, Bifidobacteriales Infections/microbiology, Bifidobacterium/metabolism, Carbohydrates/chemistry, Chromatography, High Pressure Liquid/methods, Female, Gastrointestinal Tract/microbiology, Humans, Infant, Newborn, Intestines/microbiology, Japan, Milk, Human/metabolism, Molecular Sequence Data, Monosaccharides, Oligosaccharides/chemistry/metabolism, Time Factors	Pathogenicity
Metabolism	22612915	Characterization of a Panela cheese with added probiotics and fava bean starch.	Escobar MC, Van Tassell ML, Martinez-Bustos F, Singh M, Castano-Tostado E, Amaya-Llano SL, Miller MJ	J Dairy Sci	10.3168/jds.2011-4655	2012	Bifidobacterium/metabolism, Cheese/standards, Food Microbiology/methods, Food Technology/methods, Hydrolysis, Lactobacillus/metabolism, Probiotics/metabolism, Starch/metabolism, *Vicia faba/metabolism	Biotechnology
Pathogenicity	22897719	Identification and accurate quantitation of biological oligosaccharide mixtures.	Strum JS, Kim J, Wu S, De Leoz ML, Peacock K, Grimm R, German JB, Mills DA, Lebrilla CB	Anal Chem	10.1021/ac301128s	2012	Bifidobacterium/enzymology, Chromatography, High Pressure Liquid, Deuterium Exchange Measurement, Gastrointestinal Tract/microbiology, Glycoside Hydrolases/metabolism, Humans, Mass Spectrometry, Milk, Human/chemistry, Oligosaccharides/*analysis	Enzymology
Phylogeny	23315725	Isolation of a bifidogenic peptide from the pepsin hydrolysate of bovine lactoferrin.	Oda H, Wakabayashi H, Yamauchi K, Sato T, Xiao JZ, Abe F, Iwatsuki K	Appl Environ Microbiol	10.1128/AEM.03343-12	2013	Animals, Bifidobacterium/drug effects/growth & development, Cattle, Growth Inhibitors/isolation & purification/pharmacology, Hydrolysis, Intercellular Signaling Peptides and Proteins/isolation & purification/pharmacology, Lactoferrin/metabolism, Microbial Sensitivity Tests, Pepsin A/metabolism	Enzymology
Metabolism	25089712	Two beta-galactosidases from the human isolate Bifidobacterium breve DSM 20213: molecular cloning and expression, biochemical characterization and synthesis of galacto-oligosaccharides.	Arreola SL, Intanon M, Suljic J, Kittl R, Pham NH, Kosma P, Haltrich D, Nguyen TH	PLoS One	10.1371/journal.pone.0104056	2014	Bacterial Proteins/genetics/metabolism, Bifidobacterium/enzymology/genetics/isolation & purification, Chaperonin 10/genetics/metabolism, Chaperonin 60/genetics/metabolism, Cloning, Molecular, Escherichia coli/genetics/metabolism, Galactose/metabolism, Gene Expression, Glucose/metabolism, Humans, Hydrogen-Ion Concentration, Infant, Intestines/microbiology, Isoenzymes/genetics/metabolism, Kinetics, Lactose/metabolism, Molecular Weight, Oligosaccharides/biosynthesis, Protein Multimerization, Temperature, beta-Galactosidase/genetics/metabolism	Enzymology
	25866754	A Novel Lactobacillus casei LP1 Producing 1,4-Dihydroxy-2-Naphthoic Acid, a Bifidogenic Growth Stimulator.	Kang JE, Kim TJ, Moon GS	Prev Nutr Food Sci	10.3746/pnf.2015.20.1.78	2015
Pathogenicity	26083838	RNA of Enterococcus faecalis Strain EC-12 Is a Major Component Inducing Interleukin-12 Production from Human Monocytic Cells.	Nishibayashi R, Inoue R, Harada Y, Watanabe T, Makioka Y, Ushida K	PLoS One	10.1371/journal.pone.0129806	2015	Cells, Cultured, Enterococcus faecalis/immunology, Gram-Positive Bacterial Infections/immunology/microbiology, Humans, Interleukin-12/immunology, Leukocytes, Mononuclear/immunology/microbiology, Monocytes/immunology/microbiology, RNA, Bacterial/*immunology	Biotechnology
Genetics	26142063	Complete genome sequence of Bifidobacterium breve JCM 1192(T) isolated from infant feces.	Morita H, Toh H, Oshima K, Nakano A, Omori E, Hattori Y, Arakawa K, Suda W, Honda K, Hattori M	J Biotechnol	10.1016/j.jbiotec.2015.06.414	2015	Base Composition, Bifidobacterium/genetics, Feces/microbiology, Genome Size, Genome, Bacterial, Humans, Infant, Molecular Sequence Annotation, Molecular Sequence Data, Sequence Analysis, DNA/methods	Pathogenicity
Pathogenicity	26689225	Interaction of mouse splenocytes and macrophages with bacterial strains in vitro: the effect of age in the immune response.	Van Beek AA, Hoogerland JA, Belzer C, De Vos P, De Vos WM, Savelkoul HF, Leenen PJ	Benef Microbes	10.3920/BM2015.0094	2015	Age Factors, Aging/drug effects/immunology, Animals, Bifidobacterium/physiology, Humans, Interleukin-10/immunology, Interleukin-6/immunology, Lactobacillus/physiology, Macrophages/drug effects/immunology, Male, Mice, Mice, Inbred C57BL, Probiotics/pharmacology, Spleen/cytology/drug effects/immunology, Tumor Necrosis Factor-alpha/immunology
Enzymology	26749248	In vitro and in vivo evaluation of the prebiotic effect of raw and roasted almonds (Prunus amygdalus).	Liu Z, Wang W, Huang G, Zhang W, Ni L	J Sci Food Agric	10.1002/jsfa.7604	2016	Animals, Cecum/microbiology, Cooking, Enterococcus/isolation & purification, Feces/microbiology, Gastrointestinal Contents, Male, Prebiotics, Prunus dulcis/*chemistry, Rats, Rats, Wistar, Specific Pathogen-Free Organisms	Phylogeny
	27774093	Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1(-/Delta7) Mice.	van Beek AA, Sovran B, Hugenholtz F, Meijer B, Hoogerland JA, Mihailova V, van der Ploeg C, Belzer C, Boekschoten MV, Hoeijmakers JH, Vermeij WP, de Vos P, Wells JM, Leenen PJ, Nicoletti C, Hendriks RW, Savelkoul HF	Front Immunol	10.3389/fimmu.2016.00408	2016
Metabolism	28115383	Mechanistic Study of Utilization of Water-Insoluble Saccharomyces cerevisiae Glucans by Bifidobacterium breve Strain JCM1192.	Keung HY, Li TK, Sham LT, Cheung MK, Cheung PCK, Kwan HS	Appl Environ Microbiol	10.1128/AEM.03442-16	2017	ATP-Binding Cassette Transporters/genetics/metabolism, Bacterial Proteins/genetics/metabolism, Bifidobacterium breve/drug effects/genetics/growth & development/metabolism, Cell Wall/chemistry/metabolism, Dextrins/pharmacology, Glucans/metabolism, Glycogen/pharmacology, Glycoside Hydrolases/genetics/metabolism, Hydrolysis, Maltose/metabolism/pharmacology, Mutation, Saccharomyces cerevisiae/*chemistry, Solubility, Synbiotics, Water, beta-Glucans/metabolism	Pathogenicity
Metabolism	28780103	Human milk oligosaccharide consumption by probiotic and human-associated bifidobacteria and lactobacilli.	Thongaram T, Hoeflinger JL, Chow J, Miller MJ	J Dairy Sci	10.3168/jds.2017-12753	2017	Animals, Bifidobacterium/metabolism, Humans, Lactobacillus/metabolism, Milk, Human/chemistry, Oligosaccharides/metabolism, Probiotics/metabolism	Pathogenicity
Phylogeny	29116036	Bifidobacterium callitrichidarum sp. nov. from the faeces of the emperor tamarin (Saguinus imperator).	Modesto M, Michelini S, Sansosti MC, De Filippo C, Cavalieri D, Qvirist L, Andlid T, Spiezio C, Sandri C, Pascarelli S, Sgorbati B, Mattarelli P	Int J Syst Evol Microbiol	10.1099/ijsem.0.002472	2017	Aldehyde-Lyases/chemistry, Animals, Bacterial Typing Techniques, Base Composition, Bifidobacterium/classification/genetics/isolation & purification, DNA, Bacterial/genetics, Fatty Acids/chemistry, Feces/microbiology, Multilocus Sequence Typing, Peptidoglycan/chemistry, Phylogeny, RNA, Ribosomal, 16S/genetics, Saguinus/*microbiology, Sequence Analysis, DNA	Transcriptome
Enzymology	30518022	Highly Selective Production of Compound K from Ginsenoside Rd by Hydrolyzing Glucose at C-3 Glycoside Using beta-Glucosidase of Bifidobacterium breve ATCC 15700.	Zhang R, Huang XM, Yan HJ, Liu XY, Zhou Q, Luo ZY, Tan XN, Zhang BL	J Microbiol Biotechnol	10.4014/jmb.1808.08059	2019	Bacterial Proteins/genetics/metabolism, Bifidobacterium breve/genetics/metabolism, Biotransformation, Cloning, Molecular, Enzyme Assays, Enzyme Stability, Escherichia coli/genetics, Gene Expression Regulation, Bacterial, Ginsenosides/biosynthesis/chemistry/metabolism, Glucose/metabolism, Glycosides, Hydrogen-Ion Concentration, Hydrolysis, Kinetics, Monosaccharides/metabolism, Recombinant Proteins/genetics/isolation & purification/metabolism, Substrate Specificity, beta-Glucosidase/genetics/isolation & purification/*metabolism	Metabolism
	31861103	Effects of Linoleic Acid on Gut-Derived Bifidobacterium breve DSM 20213: A Transcriptomic Approach.	Senizza A, Callegari ML, Senizza B, Minuti A, Rocchetti G, Morelli L, Patrone V	Microorganisms	10.3390/microorganisms7120710	2019
Metabolism	32265475	Linoleic acid induces metabolic stress in the intestinal microorganism Bifidobacterium breve DSM 20213.	Senizza A, Rocchetti G, Callegari ML, Lucini L, Morelli L	Sci Rep	10.1038/s41598-020-62897-w	2020	Bifidobacterium breve/growth & development/metabolism, Biosynthetic Pathways, Intestines/microbiology, Linoleic Acid/*metabolism, Linoleic Acids, Conjugated/metabolism, Metabolome, Oxidation-Reduction, Oxidative Stress, Stress, Physiological	Stress
	32545606	Evaluation of Bifidobacteria and Lactobacillus Probiotics as Alternative Therapy for Salmonella typhimurium Infection in Broiler Chickens.	El-Sharkawy H, Tahoun A, Rizk AM, Suzuki T, Elmonir W, Nassef E, Shukry M, Germoush MO, Farrag F, Bin-Jumah M, Mahmoud AM	Animals (Basel)	10.3390/ani10061023	2020
Biotechnology	33134584	Impact of prebiotics on equol production from soymilk isoflavones by two Bifidobacterium species.	Mustafa SE, Mustafa S, Ismail A, Abas F, Abd Manap MY, Ahmed Hamdi OA, Elzen S, Nahar L, Sarker SD	Heliyon	10.1016/j.heliyon.2020.e05298	2020
Pathogenicity	34024895	Safety Evaluation of Bifidobacterium breve IDCC4401 Isolated from Infant Feces for Use as a Commercial Probiotic.	Choi IY, Kim J, Kim SH, Ban OH, Yang J, Park MK	J Microbiol Biotechnol	10.4014/jmb.2103.03041	2021	Anti-Bacterial Agents/pharmacology, Bacterial Proteins/metabolism, Bifidobacterium breve/drug effects/genetics/isolation & purification, Drug Resistance, Bacterial, Feces/microbiology, Food Safety, Genes, Bacterial, Genome, Bacterial/genetics, Humans, Infant, Lactic Acid/metabolism, Microbial Sensitivity Tests, Probiotics, Vancomycin/pharmacology	Phylogeny
Phylogeny	34721319	Comparison of 16S rRNA Gene Based Microbial Profiling Using Five Next-Generation Sequencers and Various Primers.	Park C, Kim SB, Choi SH, Kim S	Front Microbiol	10.3389/fmicb.2021.715500	2021

Reference

@id	authors	catalogue	doi/url	title	journal	pubmed
8482	Curators of the DSMZ	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 20213)	https://www.dsmz.de/collection/catalogue/details/culture/DSM-20213
20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.		10.1099/ijsem.0.004332	List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.		10.1016/j.syapm.2013.11.002	StrainInfo introduces electronic passports for microorganisms.	Syst Appl Microbiol. 37: 42-50 2014	24321274
42088	Curators of the CIP		https://brclims.pasteur.fr/brcWeb/souche/detail/1/10175
66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann		https://diaspora-project.de/progress.html#genomes	Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg		10.1093/nar/gkaa1025	BRENDA, the ELIXIR core data resource in 2021: new developments and updates	Nucleic Acids Res. 49: D498-D508 2020	33211880
67770	Curators of the JCM		https://jcm.brc.riken.jp/en/
68371				Automatically annotated from API 50CH acid
69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.		https://microbeatlas.org/	MicrobeAtlas 1.0 beta
69480	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann		https://diaspora-project.de/progress.html#genomes	Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)