To improve the thrust by the O/F shift, which is one of the weak points of the hybrid rocket, a method with a variable oxidizer strength has been proposed. In this study, the superiority of this type of hybrid rocket over the conventional hybrid rocket without variable oxidizer supply was compared through several launch vehicle designs, such as altitude maximization by vertical launch and downrange extension problems with an optimized launch angle. A multi-objective evolutionary algorithm and the multi-disciplinary evaluation method of the launch vehicle were applied.