Development of Probiotics for Helicobacter pyloni Infection

Katsunori KIMURA; Ichiko SAKAMOTO; Muneki IGARASHI; Atsushi TAKAGI; Takeshi MIWA; Yuji AIBA; Yasuhiro KOGA

doi:10.12938/bifidus1996.22.1

Development of Probiotics for Helicobacter pyloni Infection

Katsunori KIMURA, Ichiko SAKAMOTO, Muneki IGARASHI, Atsushi TAKAGI, Takeshi MIWA, Yuji AIBA, Yasuhiro KOGA

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Keywords: Lactobacillus gasseri, Helicobacter pylori, probiotics, LG21, mucosal inflammation

JOURNAL FREE ACCESS

2003 Volume 22 Issue 1 Pages 1-4

DOI https://doi.org/10.12938/bifidus1996.22.1

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Abstract

To develop probiotics for Helicobacter pylori infection, we screened 203 Latobacillus strains. Lactobacillus gasseri OLL2716 (LG21) was selected as the most effective strain to inhibit the growth of H. pylori by in vitro tests and animal study. We examined the effects of yogurt containing LG21 on H. pylori infection in humans. The intake of yogurt containing LG21 both decreases the number of H. pylori and also reduces mucosal inflammation. LG21 was shown to be effective as a probiotic for H. pylori infection.

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