In ferrets (Mustela putorius furo), the incidence of hemangiosarcomas is low. Cutaneous hemangiosarcomas in ferrets have been reported as in other organs, but the clinical and diagnostic details are unclear. The present case developed an ulcerative lesion on the dorsal skin of the metatarsal region of the left hindlimb, and the limb was surgically amputated due to exacerbation of the lesion. A diagnosis of hemangiosarcoma was obtained based on histopathological examinations. The examinations revealed proliferation of endothelial celllike pleomorphic cells, which were immunohistochemically positive for Factor YIII-related antigen. The present case achieved long-term survival without recurrence or distant metastasis after six months, and is currently showing good prognosis. We describe details of clinical progress usefulness of immunohistochemical staining, and possibility of good prognosis in a ferret cutaneons hemangiosarcoma.