Percutaneous fine needle aspiration biopsy of lung masses is a simple and the most frequently used interventional procedure in radiologic department. Its use is progressively increased, relating to the improvemt of fluoroscopy and types of aspiration needle, and the advances in cyto-pathology. Over a period of recent 2 years, 21 cases of lung mass underwent percutaneous aspiration biopsy were analysed. 14 cases were proven as malignancy. 3 cases were benign lesions. Open lung biopsy and operation permit the exact pathology of the remaining 4 cases as malignancy. The overall diagnostic accuracy was 81% (17/21). Author recommended that the percutaneous fine needle aspiration biopsy must be inital procedure in diagnostic work-up of pulmonary masses.