Abstract

We investigated the effects of a buckwheat protein product (BWP), soy protein isolate (SPI) and casein on the plasma cholesterol level and fecal steroid excretion in rats fed on a cholesterol-free diet. The consumption of BWP suppressed plasma cholesterol by enhancing the fecal excretion of both neutral and acidic steroids. These effects of BWP were stronger than those of SPI.

References

1) Kayashita, J., Shimaoka, I., and Nakajoh, M., Hypocholesterolemic effect of buckwheat protein extract in rats fed cholesterol enriched diets. Nutr. Res., 15, 691-698 (1995).

2) Kayashita, J., Shimaoka, I., Nakajoh, M., Yamazaki, M., and Kato, N., Consumption of buckwheat protein lowers plasma cholesterol and raises fecal neutral sterols in cholesterol-fed rats because of its low digestibility. J. Nutr., 127, 1395-1400 (1997).

3) Tomotake, H., Shimaoka, I., Kayashita, J., Yokoyama, F., Nakajoh, M., and Kato, N., A buckwheat protein product suppresses gallstone formation and plasma cholesterol more strongly than soy protein isolate in hamsters. J. Nutr., 130, 1670-1674 (2000).

4) Nagata, Y., Tanaka, K., and Sugano, M., Serum and liver cholesterol levels of rats and mice fed soy-bean protein or casein. J. Nutr. Sci. Vitaminol., 27, 583-593 (1981).

5) Nagata, Y., Ishiwaki, N., and Sugano, M., Studies on the mechanism of the antihypercholesterolemic action of soy protein and soy protein-type amino acid mixtures in relation to their casein counterparts in rats. J. Nutr., 112, 1614-1625 (1982).

6) Ikeda, I., Tomari, Y., and Sugano, M., Interrelated effects of dietary fiber and fat on lymphatic cholesterol and triglyceride absorption in rats. J. Nutr., 119, 1383-1387 (1989).

7) Miettinen, T.A., Ahrens Jr., E.H., and Grundy, S.M., Quantitative isolation and gas-liquid chromatographic analysis of total dietary and fecal neutral steroids. J. Lipid Res., 6, 411-424 (1965).

8) Duncan, D.B., Multiple range test for correlated and heteroscedastic means. Biometrics, 13, 164-176 (1957).

9) Huff, M.W., and Carroll, K.K, Effects of dietary protein on turnover, oxidation, and absorption of cholesterol, and on steroid excretion in rabbits. J. Lipid Res., 21, 546-558 (1980).

10) Sugano, M., Goto, S., Yamada, Y., Yoshida, K., Hashimoto, Y., Matsuo, T., and Kimoto M., Cholesterol-lowering activity of various undigested fractions of soybean protein in rats. J. Nutr., 120, 977-985 (1990).

This content is only available as a PDF.
This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)