The Japanese Journal of Genetics
Online ISSN : 1880-5787
Print ISSN : 0021-504X
ISSN-L : 0021-504X
ABSENCE OF CORRELATION BETWEEN DNA REPAIR IN ULTRAVIOLET IRRADIATED MAMMALIAN CELLS AND LIFE SPAN OF THE DONOR SPECIES
HATAO KATOMASASHI HARADAKIMIYUKI TSUCHIYAKAZUO MORIWAKI
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1980 Volume 55 Issue 2 Pages 99-108

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Abstract

The amounts of unscheduled DNA synthesis in fibroblasts originating from 34 species in 11 orders of mammals, after 10Jm-2 UV irradiation, were assayed by autoradiography. Genome size of the species was determined by cytophotometric measurements of DNA contents of the cultured cells and the ability of unscheduled DNA synthesis per unit amount of DNA was computed. There was no correlation between repair potentials and life span, denying the presence of the correlation suggested by Hart and Setlow on 7 species.

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© The Genetics Society of Japan
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