11 January 2013
Megaloblastic hematopoiesis in a 20 year old pregnant female
Evan T. Trivette, Kyle Hoedebecke, Cristóbal S. Berry-Cabán, Brandy R. JacobsDOI: 10.12659/AJCR.883734
Am J Case Rep 2013; 14:10-12
Abstract
Background: Nitrous oxide can cause disordered blood cell proliferation and lead to pancytopenia and altered immune function.
Case Report: A young pregnant female patient presented after binge nitrous oxide abuse with altered mental status and abnormal vital signs. From her initial assessment she was noted to have pancytopenia and was found to have megaloblastic, hyper-cellular changes in a subsequent bone marrow biopsy. This presentation was determined to be secondary to toxic effects after heavy use of nitrous oxide.
Conclusions: Nitrous oxide exposure, including use as an inhalant, over 12 hours can lead to bone marrow abnormalities such as megaloblastic hematopoiesis.
Keywords: Pregnancy, megaloblastic hematopoiesis, Hematopoiesis, Nitrous Oxide - toxicity
In Press
Case report
Clinical Progression and Manifestations of H Syndrome: A Case Report of Failed Treatment OptionAm J Case Rep In Press; DOI: 10.12659/AJCR.944198
Case report
Successful Treatment of Cervical Spondylolysis with Grade-II Spondylolisthesis using Single-Level ACDF: A C...Am J Case Rep In Press; DOI: 10.12659/AJCR.943823
Case report
Over-the-Scope-Clip Iatrogenic Ligation of the Gastroduodenal Artery: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.943891
Case report
A 55-Year-Old Woman Presenting with a Second Diagnosis of Craniopharyngioma Following Diagnosis and Success...Am J Case Rep In Press; DOI: 10.12659/AJCR.943300
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250