RNA kink turns to the left and to the right
Abstract
A helix-loop-helix within the group I intron has most of the canonical sequence elements of a kink turn (K-turn), yet it bends in the opposite direction. The reverse K-turn kinks toward the major rather than the minor grooves of the flanking helices. This suggests that there are two distinct subclasses of tertiary structures that a K-turn secondary structure can adopt. The final structure may be specified by external factors, such as protein binding or the tertiary structural context, rather than the intrinsic conformation of the RNA.
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Footnotes
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Article and publication are at http://www.rnajournal.org/cgi/doi/10.1261/rna.7141504.
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- Accepted October 4, 2004.
- Received July 30, 2004.
- Copyright 2004 by RNA Society