Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Isoflavones and Rotenoids from the Leaves of Millettia brandisiana
Orasa PancharoenAnan AthipornchaiAmpai PanthongWalter Charles Taylor
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2008 Volume 56 Issue 6 Pages 835-838

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Abstract

A new isoflavone, 4′-γ,γ-dimethylallyloxy-5,7,2′,5′-tetramethoxyisoflavone, brandisianin A (1), was isolated from the leaves of Millettia brandisiana, along with one synthetically known isoflavone, 7,4′-di-O-prenylgenistein (2) and twelve known compounds. The structures were elucidated on the basis of extensive spectroscopic analysis. Two isolated compounds were tested for anti-inflammatory activity; 12a-hydroxy-α-toxicarol (11) showed significant anti-inflammatory activity.

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© 2008 The Pharmaceutical Society of Japan
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