Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Further Study on Dammarane-Type Saponins of Roots, Leaves, Flower-Buds, and Fruits of Panax ginseng C. A. MEYER
SHOJI YAHARAKIYOKO KAJIOSAMU TANAKA
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Keywords: Araliaceae
JOURNAL FREE ACCESS

1979 Volume 27 Issue 1 Pages 88-92

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Abstract

New saponins, named ginsenosides-Rh1 (11) and -M7cd (17) were isolated from roots and flower-buds of Ginseng, repectively. Structures of 11 and 17 were established as 6-O-β-D-glucopyranoside of 20 (S) -protopanaxatriol and 20-O-β-D-glucopyranoside of dammar-25-ene-3β, 6α, 12β, 20 (S), 24ξ-pentaol, respectively by means of carbon-13 nuclear magnetic resonance spectroscopy as well as their preparations from the known saponins. Further isolation and identification of the following dammarane-type saponins from the aerial parts of Ginseng were also reported : ginsenosides-Rb1 (1), -Rb2 (2), -Rc (4) from the leaves ; 1, 2, 4, and ginsenoside-F3 (15) from the flower-buds, and 2, 4, ginsenosides-Rd (5), -Re (6), and -Rg1 (8) from the fruits. As shown in Table II, isolation of these biologically active saponins in relatively high yields indicated the significance of the aerial parts of Ginseng as the good medicinal sources.

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