Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Hypoglycemic Agents. IV. Synthesis of 1, 4, 3-Benzoxathiazine-4, 4-dioxides
SEIGO SUZUETUTOMU IRIKURA
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1968 Volume 16 Issue 5 Pages 806-813

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Abstract

2-Hydroxybenzenesulfonamides were prepared in good yield from 2-acetoxyphenyl-sulfonylchlorides via N-acetyl-2-hydroxybenzenesulfonamides, followed by hydrolysis. The preparations of 2-alkyl, aryl, benzyl, or substituted amino-1, 4, 3-benzoxathiazine-4, 4-dioxides were described. Further 2-methyl-, or benzyl-2, 3-dihydro-1, 4, 3-benzoxathiazine-4, 4-dioxide was also prepared.

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© The Pharmaceutical Society of Japan
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