As ⁶⁷Ga is injected into the blood, ⁶⁷Ga is immediately bound to transferrin (Tf) and transported to various tissues and the Tf–⁶⁷Ga complex binds to Tf receptor on various tissues. In partial hepatectomy (PH) a part of blood in circulation is lost together with removed liver tissues, consequently the amounts of blood cells and Tf in circulation decrease. In order to investigate the effect of those decreases on ⁶⁷Ga uptake by the liver, we compared the uptake in partially hepatectomized rats with that in venesectioned rats in which only a part of blood in circulation decreased. A two-thirds PH was performed. Two milliliters of blood was venesectioned. Each treated rat was intraveneously injected with ⁶⁷Ga. The changes of erythrocyte and reticulocyte contents after PH did not differ from those after venesection (VS) at all. But ⁶⁷Ga uptake by reticulocytes significantly increased after VS but did not after PH. On the other hand, ⁶⁷Ga uptake by the liver significantly increased after PH but did not after VS. These differences must be related to the different expression of Tf receptors on the liver after PH and VS.