1963 年 83 巻 4 号 p. 422-423
The leaves of Ligularia tussilaginea MAKINO have been used from olden times as a home remedy for suppurating eruptions, same as Houttuynia cordata THUNB. The crude drug of Ligularia tussilaginea was submitted to low-pressure steam distillation and a substance with an odor of this plant was isolated, which was later identified as 2-hexanal. 2-Hexanal was effective against Staphylococcus pyogenes in 1:5000 dilution and against Trichophyton asteroides in 1:10000 dilution.