Synthesis and Antimicrobial Activity of Pyrrolyl/Pyrazolyl Arylaminosulfonylmethyl 1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles

Adivireddy Padmaja; Akkarapalli Muralikrishna; Chittoor Rajasekhar; Venkatapuram Padmavathi

doi:10.1248/cpb.59.1509

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Synthesis and Antimicrobial Activity of Pyrrolyl/Pyrazolyl Arylaminosulfonylmethyl 1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles

Adivireddy Padmaja, Akkarapalli Muralikrishna, Chittoor Rajasekhar, Venkatapuram Padmavathi

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Keywords: pyrrolyl/pyrazolyl-1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,2,4-triazole, 1,3-dipolar cycloaddition, antimicrobial activity

JOURNAL FREE ACCESS

2011 Volume 59 Issue 12 Pages 1509-1517

DOI https://doi.org/10.1248/cpb.59.1509

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Abstract

A new class of pyrrolyl/pyrazolyl arylaminosulfonylmethyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles, and 1,2,4-triazoles were prepared and tested for antimicrobial activity. Amongst the tested compounds, 5c displayed high antimicrobial activity.

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