Loniceroside C, an Antiinflammatory Saponin from Lonicera japonica

Wie Jong Kwak; Chang Kyun Han; Hyeun Wook Chang; Hyun Pyo Kim; Sam Sik Kang; Kun Ho Son

doi:10.1248/cpb.51.333

Notes

Loniceroside C, an Antiinflammatory Saponin from Lonicera japonica

Wie Jong Kwak, Chang Kyun Han, Hyeun Wook Chang, Hyun Pyo Kim, Sam Sik Kang, Kun Ho Son

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Keywords: Lonicera japonica, Caprifoliaceae, triterpenoid saponin, loniceroside C, antiinflammatory activity

JOURNAL FREE ACCESS

2003 Volume 51 Issue 3 Pages 333-335

DOI https://doi.org/10.1248/cpb.51.333

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Abstract

A new triterpenoid saponin, loniceroside C was isolated from the aerial parts of Lonicera japonica. Its structure was established to be 3-O-β-D-glucopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl (1→2)-[β-D-xylopyranosyl(1→6)]-β-D-glucopyranosyl ester by spectroscopic techniques and chemical transformations. Loniceroside C showed in vivo antiinflammatory activity against mouse ear edema provoked by croton oil.

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