Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
INHIBITORY ACTIVITY OF XANTHONE DERIVATIVES ISOLATED FROM SOME GUTTIFERAEOUS PLANTS AGAINST DNA TOPOSIOMERASES I AND II
Hideaki TOSAMunekazu IINUMAToshiyuki TANAKAHiroshi NOZAKIShougo IKEDAKen TSUTSUIKimiko TSUTUSIMasashi YAMADAShiho FUJIMORI
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1997 Volume 45 Issue 2 Pages 418-420

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Abstract

A xanthone derivative, subelliptenone F, and the related compounds showed an intensive inhibitory effect against topoisomerases I and II in in vitro experiments. These xanthones are prospective lead compounds for anticancer drugs.

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© The Pharmaceutical Society of Japan
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