CAMELLIIN B AND NOBOTANIN I, MACROCYCLIC ELLAGITANNIN DIMERS AND RELATED DIMERS, AND THEIR ANTITUMOR ACTIVITY

Takashi YOSHIDA; Tong CHOU; Kumiko HABA; Yoshiaki OKANO; Tetsuro SHINGU; Ken-ici MIYAMOTO; Ryozo KOSHIURA; Takuo OKUDA

doi:10.1248/cpb.37.3174

Takashi YOSHIDA, Tong CHOU, Kumiko HABA, Yoshiaki OKANO, Tetsuro SHINGU, Ken-ici MIYAMOTO, Ryozo KOSHIURA, Takuo OKUDA

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Keywords: camelliin B, Camellia japonica, nobotanin G, nobotanin H, nobotanin I, Heterocentron roseum, tannin, hydrolyzable tannin, macrocyclic dimer, antitumor activity

JOURNAL FREE ACCESS

1989 Volume 37 Issue 11 Pages 3174-3176

DOI https://doi.org/10.1248/cpb.37.3174

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Abstract

Camelliin B and nobotanin I, dimeric hydrolyzable tannins of a new class having macrocyclic structures, were isolated from Camellia japonica and Heterocentron roseum, respectively. Nobotanin G and H of the structures related to nobotanin I, were also obtained from H. roseum. Camelliin B and also woodfordin C, a macrocyclic dimer from Woodfordia fruticosa, exhibited marked host-mediated antitumor activities.

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