Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
7α-Methoxylation of Cephalosporins
YUKIO SUGIMURA, KIMIO IINO, YUJI IWANO, TOKIO SAITO, TETSUO HIRAOKA
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Keywords: trimethylchlorosilane
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1977 Volume 25 Issue 2 Pages 369-370

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Abstract

7α-Methoxy-7β-vinylacetamidocephalosporins were synthesized from 7β-(ω-halocrotonyl) aminocephalosporins using phosphorus pentachloride and lithium methoxide by a 1, 6-elimination reaction.

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