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Laparoscopic Pancreatectomy for Solid Pseudo-Papillary Tumors of the Pancreas is a Suitable Technique; Our Experience with Long-Term Follow-up and Review of the Literature

  • Pancreatic Tumors
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

An Erratum to this article was published on 19 January 2011

Abstract

Background

Solid pseudopapillary tumors (SPTs) are rare pancreatic neoplasms of low malignant potential that occur mainly in young women. Only 17 cases of SPT treated laparoscopically have been published in the literature and long-term follow-up data are still lacking.

Methods

Retrospective analysis of ten patients (8 women, 2 men; mean age, 25.4 years) (DS: 12.1; minimum 11, maximum 51) who underwent laparoscopic distal pancreatectomy with a definitive histological diagnosis of SPT. Long-term follow-up data were collected.

Results

The average tumor size was 43.8 mm (minimum 20, maximum 65 mm). The mean operative time was 177.5 minutes (DS: 53.7; minimum 120, maximum 255). In all, five patients underwent distal splenopancreatectomy; five patients underwent spleen-preserving distal pancreatectomy of whom three with splenic vessel preservation and two with the Warshaw technique. The conversion rate was nil and no case of perioperative mortality was recorded. The mean hospital stay was 7 days (DS: 2.7; minimum 4, maximum 12). Six patients had an uneventful postoperative course and four had postoperative complications. Two of them underwent reoperation, and the other two had nonsurgical complications. After a median follow-up of 47 (range, 5–98) months, all patients were alive and disease-free.

Conclusions

Laparoscopic pancreatic resection is a safe and feasible procedure that could become the treatment of choice for patients affected by pancreatic SPT. Distal pancreatectomy should be performed, if possible, with spleen-preserving technique, especially in young patients. To avoid metastatic spread, laparoscopic or laparotomic biopsy should not be performed in patients affected by SPT.

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Acknowledgment

This study has been supported by the Fondazione Italiana Malattie Pancreas (FIMP) Verona, Italy. We gratefully acknowledge Alfredo F. Tonsi for his assistance with manuscript review.

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Authors and Affiliations

  1. Surgical Department, Chirurgia Generale B-Policlinico GB Rossi-Borgo Roma, Verona University, Verona, Italy

    Cavallini Alvise MD, Butturini Giovanni MD, Daskalaki Despoina MD, Salvia Roberto MD, Bassi Claudio MD & Pederzoli Paolo MD

  2. General Surgery, Baggiovara Hospital, Modena, Italy

    Melotti Gianluigi MD & Piccoli Micaela MD

Authors
  1. Cavallini Alvise MD
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  2. Butturini Giovanni MD
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  3. Daskalaki Despoina MD
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  4. Salvia Roberto MD
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  5. Melotti Gianluigi MD
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  6. Piccoli Micaela MD
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  7. Bassi Claudio MD
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  8. Pederzoli Paolo MD
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Correspondence to Butturini Giovanni MD.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1245/s10434-010-1548-4

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Alvise, C., Giovanni, B., Despoina, D. et al. Laparoscopic Pancreatectomy for Solid Pseudo-Papillary Tumors of the Pancreas is a Suitable Technique; Our Experience with Long-Term Follow-up and Review of the Literature. Ann Surg Oncol 18, 352–357 (2011). https://doi.org/10.1245/s10434-010-1332-5

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  • DOI: https://doi.org/10.1245/s10434-010-1332-5

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