Relationship between Lower Extremity Atherosclerosis and Acute Coronary SyndromeChinese Full Text
LI Yayu;WANG Tong;QU Qingxia;ZHANG Yue;LENG Yue;WANG Yiming;LIU Haixia;CHU Yinzhu;Department of Ultrasonography,the First Affiliated Hospital of Harbin Medical University;Department of Gynecology,Affiliated Tumor Hospital of Harbin Medical University;
Abstract: Background Acute coronary syndrome（ACS）,a subset of coronary heart disease（CHD）,is the most urgent and serious,and mainly associated with the rupture and bleeding of unstable coronary plaques.Since the same pathogenesis and pathological changes on peripheral atherosclerosis and coronary atherosclerosis,recently,the growing studies performed to understanding or predicting coronary atherosclerotic lesions through peripheral atherosclerotic lesions.However,the relationship between the lower extremity and CHD,especially ACS is still unclear.Objective To investigate the relationship between arteriosclerosis of lower extremities and ACS.Methods A total of 224 patients with CHD or suspected CHD from the Department of Cardiology and Cardiac Surgery of the First Affiliated Hospital of Harbin Medical University in 2020 were divided into the ACS group（n=151） and the non-ACS group（n=73）.Gender,age,height,body mass index,diabetes,hypertension,smoking,drinking,family history of CHD,family history of stroke,laboratory examination indicators [including total cholesterol（TC）,triglyceride（TG）,high-density lipoprotein cholesterol（HDL-C）,low-density lipoprotein cholesterol（LDL-C）,γ-glutamyl transpeptidase（GGT）,blood urea nitrogen,serum creatinine（Scr）],and arteriosclerosis indexes of lower extremities were compared between the two groups.Multivariate Logistic regression analysis was used to indentify the influencing factors for ACS.Results The proportion of male,height,smokers and GGT in the ACSgroup were higher than those in the non-ACS group（P ＜0.05）.The number of superficial femoral artery stenosis,anterior tibial artery stenosis,posterior tibial artery stenosis,and the total number of lower limb artery stenosis in the ACS group were also more than those in the non-ACS group,the degree of superficial femoral artery stenosis,anterior tibial artery stenosis,posterior tibial artery stenosis,and lower extremity artery plaque grade in the ACS group became more severe than those in the non-ACS group（P ＜0.05）.Additionally,incidence of thickening of artery intima-media thickness in the ACS group was higher than that in the non-ACS group（P ＜0.05）.Last,the results of multivariate Logistic regression analysis showed that the index of local arteriosclerosis of lower extremities was not an independent influencing factor of ACS（P ＞0.05）,but the total number of arterial stenosis of lower extremities was an independent influencing factor of ACS（P ＜0.05）.Conclusion The total number of arterial stenosis of lower extremities is an independent influencing factor for ACS,whereas local arteriosclerosis of lower extremities is not.
- Series：
(E) Medicine ＆ Public Health
- Subject：
Cardiovascular System Disease
- Classification Code：
R541.4;R543.5
- Mobile Reading
Read on your phone instantly
Step 1Scan QR Codes
"Mobile CNKI-CNKI Express" App
Step 2Open“CNKI Express”
and click the scan icon in the upper left corner of the homepage.
Step 3
Scan QR Codes
Read this article on your phone.
- HTML
- CAJ Download
- PDF Download
Download the mobile appuse the app to scan this coderead the article.
Tips: Please download CAJViewer to view CAJ format full text.
Download: 171 Page: 23-28 Pagecount: 6 Size: 1052K
Citation Network
Related Literature
- Similar Article
- Reader Recommendation
- Associated Author