赵玲玲，裴炬盛，韦荣泉，兰梅卉，陈海林，陈思芮，陈英

引用本文： 赵玲玲，裴炬盛，韦荣泉，兰梅卉，陈海林，陈思芮，陈英.脊柱转移瘤病人衰弱影响因素分析[J].护理研究,2022,36(4):618-623

摘要： [目的]探讨脊柱转移瘤病人衰弱影响因素，为指导外科护理干预提供理论依据。[方法]选取2020年5月—2021年5月在广西省某三级甲等肿瘤专科医院住院治疗的100例脊柱转移瘤病人作为研究对象，采用一般资料调查表、脊柱转移瘤衰弱指数（MSTFI）、营养风险筛查2002（NRS 2002）、Barthel指数进行测评。采用Spearman秩相关分析衰弱与营养指标的相关性，采用Logistic回归分析探究脊柱转移瘤病人衰弱的影响因素，[结果]脊柱转移瘤病人衰弱发生率为69%；不同年龄、家庭人均月收入、日常生活活动能力（ADL）评分、有无营养风险的病人衰弱发生率比较，差异有统计学意义（<0.05）；不同衰弱状态病人的血红蛋白（HGB）、清蛋白（ALB）、C反应蛋白（CRP）、血清前清蛋白（PA）、总蛋白（TP）比较，差异均有统计学意义（<0.05）；衰弱评分与NRS2002评分、CRP呈正相关（<0.05），与HGB、ALB、PA、TP呈负相关（<0.05）。多元Logistic回归分析显示，ADL评分、NRS2002评分、HGB、CRP、PA是脊柱转移瘤病人衰弱的影响因素。[结论]脊柱转移瘤病人衰弱发生率较高，医护人员应重视病人术前衰弱的评估，关注老年病人以及自理能力低下、有营养风险的病人，重视对相关营养指标的监测，及时采取相应的措施优化手术结果、提高病人生存质量。

关键词： 衰弱;脊柱;转移瘤;营养;影响因素;护理

课题： 广西医疗卫生适宜技术开发与推广应用项目(Array) ;广西壮族自治区卫生和计划生育委员会中医药科技专项课题(GZLC16⁃37)

ZHAO Lingling，PEI Jusheng，WEI Rongquan，LAN Meihui，CHEN Hailin，CHEN Sirui，CHEN Ying

Abstract [Objective]To investigate the influencing factors of frailty in patients with spinal metastases to provide a theoretical basis for guiding surgical nursing intervention.[Methods]From May 2020 to May 2021，a total of 100 patients with spinal metastases hospitalized in a tertiary grade A tumor hospital in Guangxi Zhuang Autonomous Region were selected as the research subjects.Use General Information Questionnaire，Metastatic Spinal Tumor Frailty Index（MSTFI），Nutritional Risk Screening 2002（NRS 2002），Barthel Index（BI），Barthel Index（BI）to assess.Use Spearman rank correlation method to analyze the correlation between frailty and nutritional indicators and logistic regression analysis to explore the influencing factors of frailty in patients with spinal metastases.[Results]The incidence of frailty in patients with spinal metastases was 69%；the difference in the incidence of frailty between patients of different ages，per capita monthly income，ADL score，with or without nutritional risk was statistically significant（<0.05）.The differences between patients with different frailty degrees in hemoglobin（HBG），albumin（ALB），C⁃Reactive Protein（CRP），prealbumin（PA），total protein（TP）were statistically significant（<0.05）.Frailty score was positively correlated with NRS2002 score and CRP（<0.05）；and negatively correlated with HGB，ALB，PA，and TP（<0.05）.Multivariate logistic regression analysis showed that ADL score，NRS2002 score，HGB，CRP，and PA were the influencing factors of frailty in patients with spinal metastases.[Conclusions]The incidence of frailty in patients with spinal metastases was high.Medical workers should pay attention to the assessment of patients' preoperative frailty，elderly patients，low self⁃care ability，and nutritional risks，and monitoring of relevant nutritional indicators，and take timely measures to optimize the surgical outcome，in order to improve the patient's quality of life.

Keywords frailty;spine;metastases;nutrition;influencing factors;nursing

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