夏菁，陈海燕，杨琴，余宁

引用本文： 夏菁，陈海燕，杨琴，余宁.维持性血液透析病人疲劳、睡眠质量及健康相关生活质量现状[J].护理研究,2022,36(1):55-59

摘要： [目的]调查维持性血液透析病人在两年随访期间的疲劳、睡眠质量及健康相关生活质量的变化。[方法]纳入76例维持性血液透析病人进行两年随访，采用慢性病治疗功能评估⁃疲劳量表、医院焦虑抑郁量表、瑞典乌普萨拉大学睡眠调查表、瑞典健康相关生活质量调查表对病人进行调查。[结果]共50例病人完成两年随访。随访组从基线水平到两年随访时虽然睡眠持续时间和入睡时间均有所改善，但疲劳、睡眠充足指数、睡眠质量、睡眠障碍无显著改善，且具有抑郁、焦虑症状的病人例数较基线水平亦无明显改变。回归分析显示，两年随访时的健康相关生活质量尚不能用基线水平的睡眠参数、白天症状、睡眠干扰因素或心理健康等来预测。[结论]维持性血液透析可改善病人部分健康相关生活质量，但对睡眠质量改善效果欠佳，睡眠和健康相关生活质量的改善可能需要系统调整风险因素和优化对症治疗。

关键词： 维持性血液透析;睡眠质量;疲劳;生活质量;影响因素;调查研究

XIA Jing，CHEN Haiyan，YANG Qin，YU Ning

Abstract [Objective]To investigate the changes in fatigue，sleep quality，and health⁃related quality of life in maintenance hemodialysis patients during a two⁃year follow⁃up period.[Methods]Totally 76 maintenance hemodialysis patients were enrolled and followed up for two years.The patients were investigated by Functional Assessment of Chronic Illness Therapy⁃Fatigue Scale，Hospital Anxiety and Depression Scale，Uppsala Sleep Inventory，Swedish Health⁃Related Quality of Life Questionnaire.[Results]Eventually 50 patients were followed up for two years.In the follow⁃up group， although sleep duration and time to fall asleep were improved from baseline to two⁃year follow⁃up，however，fatigue，sleep adequacy index，sleep quality and sleep disorders were not significantly improved，and the number of patients with depression and anxiety symptoms was also not significantly changed from baseline.Regression analysis showed that health⁃related quality of life at two years of follow⁃up could not be predicted by baseline sleep parameters， daytime symptoms， sleep disruption，or mental health.[Conclusions]Maintenance hemodialysis could improve health⁃related quality of life，but it was not effective in improving sleep quality.Improvement of sleep and health⁃related quality of life may require systematic adjustment of risk factors and optimization of symptomatic treatment.

Keywords maintenance hemodialysis（MHD）;sleep quality;fatigue;quality of life;influencing factor;investigation

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