Abstract
Background and aims: Prenatal steroids (PS) are considered important in the treatment of extremely premature infants. The study was undertaken to evaluate the impact of PS on mortality and BPD in a national cohort with a high rate of prenatal steroid tretment.
Methods: All 452 admitted infants with GA ≤ 30 weeks from a national cohort of infants with gestational age (GA) of 220 to 276 weeks and/or birth weight (BW) of 500 to 999 g were studied. 83 infants died and 376 infants who survived past day 28 were evaluated for development of BPD.
Results: Although infants with or without PS had similar GA and BW, no significant differences in mortality or development of BPD could be seen (Table 1).
* data missing for 17 infants # data missing for 13 infants
Conclusions: The study indicates that treatment with prenatal steroids have only minor effects on mortality and development of BPD in extremely premature infants.
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Bratlid, D., Farstad, T. & and The Norwegian Extreme Premature Study Group. 440 Prenatal Maternal Steroid Treatment - Effect on Mortality and Bronchopulmonary Dysplasia (BPD) in Extremely Premature Infants. Pediatr Res 68 (Suppl 1), 226 (2010). https://doi.org/10.1203/00006450-201011001-00440
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DOI: https://doi.org/10.1203/00006450-201011001-00440