关键词: 慢性胰腺炎, 胰管结石, 个体化治疗, 内镜, 外科手术, 微创外科

Abstract:

Objective  To explore the application of ERCP and other surgical procedures under the concept of minimally invasive surgery, individual choice of the most appropriate operation, to improve the treatment effect of chronic pancreatitis with pancreatic duct stones. Methods  The clinical data of 38 patients with chronic  pancreatitis combined pancreatic duct stones who received endotherapy and surgical managements in our hospital from Feb. 2007 to Mar. 2014 were retrospectively analyzed. Results  Of the 38 patients, 32 patient (84.2%) received endotherapy, and 27 cases were successful. Surgical managements performed for 11 cases  (including 5 cases of endoscopic treatment failure). Effective rate was 85.2% (23/27) in full endotherapy and 72.7% (8/11) in surgical managements. Before and after the two treatments, changes of diabetes mellitus and diarrhea were not obvious. There was no perioperative deaths. During the follow-up 1 case died of diabetes renal failure, 1 case died of pancreatic cancer. Conclusion  After diagnosis of chronic pancreatitis with pancreatic duct stones, comprehensive treatment under the concept of minimally invasive surgery is suggested. Minimally invasive treatment with endoscopic technique and small invasive operation mode as far as possible to retain the pancreatic tissues and functions, which can obtain satisfactory therapeutic effect.

Key words: chronic pancreatitis, pancreatic duct stones, individualized treatment, endoscopy, surgical procedures, minimally invasive surgery