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Brain Damage in Diabetes Mellitus

Published online by Cambridge University Press:  29 January 2018

R. N. Bale*
Affiliation:
St. James' Hospital, Portsmouth, PO4 8LD; Department of Clinical Psychiatry, The United Birmingham Hospitals, The General Hospital, Steelhouse Lane, Birmingham, 4

Extract

Several previous studies have demonstrated involvement of the central nervous system in diabetes mellitus. Reske-Nielsen and Lundbaek (1963) gave a description of cerebral changes seen in an autopsy study of three cases of long term diabetes and considered these to contribute a diabetic encephalopathy. Lawrence et al. (1942) demonstrated lesions in the brain following fatal hypoglycaemia, and Fineberg and Altschul (1952) described cases in which permanent brain damage followed non-fatal hypoglycaemia. Grunnet (1963) found cerebral atherosclerosis to develop at an earlier age and more severely in the diabetic than the non-diabetic, and a higher incidence of cerebrovascular accident was found in diabetic than non-diabetic subjects by Alex et al. (1962).

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1973 

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