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Globule Leukocyte And Mast Cell in Bile Ducts of Cattle Naturally Infected with Liver Flukes

„Globule“ leukocyter och mastceller i gallgångarna hos nöt spontant infekterade med leverflundra

Abstract

In n previous report dealing with the pathology of bovine fascio-liasis the author described an unknown cell type in the epithelium of bile ducts. The histological and histochemical investigations published in this paper suggest that the cell may be considered a globule leukocyte. Globule leukocytes are rare in uninfected livers but are occurring in abundance in main bile ducts of cattle with spontaneous fascioliasis and also in small perilobular ducts in dicrocoeliasis. Liver fluke infection causes an increase in the population of subepithelial mast cells. Mast cell and globule leukocyte present similarities In their cytochemical properties. However, at low pH toluldinc blue shows a stronger but Alcian blue a weaker affinity for mast cells than for globule leukocytes.

Sammanfattning

I en tidigare publikation om patologin hos nöt med fascioliasis har författaren beskrivit en okänd celltyp i gallgångsepitelet. I denna artikel publicerade histologiska och histokemiska undersökningar visar, att denna cell bör uppfattas representera en cell av typen „globule“ leukocyt. „Globule“ leukocyt förekommer sparsamt i icke infekterade levrar, men rikligt i de större gallgångsförgreningarna hos nöt med spontan fascioliasis och dessutom i smärre perilobulära gallgångar hos nöt med dicrocoeliasis. Infektion med leverflundra orsakar en ökning av populationen med avseende på subepiteliala mastceller. Mastceller och „globule“ leukocyter presentera analoga cytokemiska egenskaper. Toluidin blått visar emellertid vid låg pH en starkare, däremot Alcian blått en svagare affinität för mastceller än för „globule“ leukocyter.

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Rahko, T. Globule Leukocyte And Mast Cell in Bile Ducts of Cattle Naturally Infected with Liver Flukes. Acta Vet Scand 11, 219–227 (1970). https://doi.org/10.1186/BF03547982

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  • DOI: https://doi.org/10.1186/BF03547982