Abstract: Objective To explore regulative effect of perceived social support on the relationship between activities of daily living and anxiety among stroke patients for the improvement of management of community stroke patients.Methods A total of 800 stroke patients were selected from 22 communities in 5 cities of Liaoning province with convenient sampling.A self-designed questionnaire,Self Rating Anxiety Scale,Activities of Daily Living Scale,and Perceived Social Support Scale were used in a household face-to-face interview and SPSS 11.5 software was used in data analyses.Results The average scores of activities of daily living,perceived society support,and anxiety were 67.69±24.37,60.05±13.58,and 55.70±11.06 among the patients.Correlation analysis results showed that activities of daily living(r=-0.29,P <0.05) and perceived social support(r=-0.22,P <0.05) were associated with anxiety; linear multiple regression analysis revealed that perceived social support and activities of daily living had a significantly interactive effect on anxiety among the patients(β=-0.11,P <0.05).Conclusion Activities of daily living and perceived organizational support are predictors of anxiety and perceived social support has a regulative effect on the relationship between activities of daily living and anxiety among stroke patients.