Abstract: ObjectiveTo explore the knowledge,attitude,occupational protection for AIDS and their related factors among medical workers in Jiangsu province. MethodsMedical workers were chosen from three health institutions of different grade in Taixing,Danyang and Zhangjiagang city with stratified sampling and investigated with a questionnaire. ResultsThe overall awareness rate of AIDS knowledge among the medical professionals was 81.41% and 36.1% of the professionals were still afraid of AIDS,while most of them(83.9%)would not refuse to treat an AIDS patient.After human immunodeficiency virus(HIV)/AIDS occupational exposure,the total rate of correct self-protection practice among the professionals was only 67.8%.Age,education level,professional title,specialities,and whether being trained before were related with the awareness of AIDS knowledge.Gender,age,the grade of the hospital,specialities,and the awareness of the risk of HIV infection were associated with the attitude towards AIDS.Meanwhile,whether the doctors would treat AIDS patients was directly influenced by the doctors'attitude towards AIDS patients(r=0.88,P=0.001).The rate of correct self-protection practice was affected by training status,whether diagnosing cases of HIV/AIDS,and working department. ConclusionThe knowledge related to AIDS is incomprehensive among medical professionals and the risk of HIV infection still exists.The protective behaviors need to be improved among medical professionals.