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Stem Cell Trafficking During Endometriosis: May Epigenetics Play a Pivotal Role?

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References

  1. Pluchino N, Taylor HS. Endometriosis and stem cell trafficking. Reprod Sci. 2016;23(12):1616–1619.

    Article  CAS  Google Scholar 

  2. Hufnagel D, Li F, Cosar E, Krikun G, Taylor HS. The role of stem cells in the etiology and pathophysiology of endometriosis. Semin Reprod Med. 2015;33(5):333–340.

    Article  CAS  Google Scholar 

  3. Santamaria X, Massasa EE, Taylor HS. Migration of cells from experimental endometriosis to the uterine endometrium. Endocrinology. 2012;153(11):5566–5574.

    Article  CAS  Google Scholar 

  4. Signorile PG, Baldi F, Bussani R, et al. Embryologic origin of endometriosis: analysis of 101 human female fetuses. J Cell Physiol. 2012;227(4):1653–1656.

    Article  CAS  Google Scholar 

  5. Laganà AS, Sturlese E, Retto G, Sofo V, Triolo O. Interplay between misplaced Mu¨llerian-derived stem cells and peritoneal immune dysregulation in the pathogenesis of endometriosis. Obstet Gynecol Int. 2013;2013:527041.

  6. Du H, Taylor HS. Contribution of bone marrow-derived stem cells to endometrium and endometriosis. Stem Cells. 2007; 25(8):2082–2086.

    Article  CAS  Google Scholar 

  7. Taylor HS. Endometrial cells derived from donor stem cells in bone marrow transplant recipients. JAMA. 2004;292(1):81–85.

    Article  CAS  Google Scholar 

  8. Guo SW. Association of endometriosis risk and genetic polymorphisms involving sex steroid biosynthesis and their receptors: a meta-analysis. Gynecol Obstet Invest. 2006;61(2):90–105.

    Article  CAS  Google Scholar 

  9. Rahmioglu N, Nyholt DR, Morris AP, Missmer SA, Montgomery GW, Zondervan KT. Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets. Hum Reprod Update. 2014;20(5): 702–716.

    Article  CAS  Google Scholar 

  10. Borghese B, Zondervan KT, Abrao MS, Chapron C, Vaiman D. Recent insights on the genetics and epigenetics of endometriosis. Clin Genet. 2016. doi:10.1111/cge.12897.

    Google Scholar 

  11. Andersson KL, Bussani C, Fambrini M, et al. DNA methylation of HOXA10 in eutopic and ectopic endometrium. Hum Reprod. 2014;29(9):1906–1911.

    Article  CAS  Google Scholar 

  12. Brueggmann D, Jaque JM, Lee AW, Pearce CL, Templeman C. Expression of Wnt signaling pathway genes in human endometriosis tissue: a pilot study. Eur J Obstet Gynecol Reprod Biol. 2016;199:214–215.

    Article  CAS  Google Scholar 

  13. Kobayashi H, Iwai K, Niiro E, Morioka S, Yamada Y. Fetal programming theory: implication for the understanding of endometriosis. Hum Immunol. 2014;75(3):208–217.

    Article  CAS  Google Scholar 

  14. Kokcu A. A current view of the role of epigenetic changes in the aetiopathogenesis of endometriosis. J Obstet Gynaecol. 2016; 36(2):153–159.

    Article  CAS  Google Scholar 

  15. Adammek M, Greve B, Ka¨ssens N, et al. MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors. Fertil Steril. 2013;99(5): 1346-1355.e5.

    Google Scholar 

  16. Eggers JC, Martino V, Reinbold R, et al. microRNA miR-200b affects proliferation, invasiveness and stemness of endometriotic cells by targeting ZEB1, ZEB2 and KLF4. Reprod Biomed Online. 2016;32(4):434–445.

    Article  CAS  Google Scholar 

  17. Kubarek L, Jagodzinski PP. Epigenetic up-regulation of CXCR4 and CXCL12 expression by 17 beta-estradiol and tamoxifen is associated with formation of DNA methyltransferase 3B4 splice variant in Ishikawa endometrial adenocarcinoma cells. FEBS Lett. 2007;581(7):1441–14418.

    Article  CAS  Google Scholar 

  18. Wu Y, Starzinski-Powitz A, Guo SW. Prolonged stimulation with tumor necrosis factor-alpha induced partial methylation at PR-B promoter in immortalized epithelial-like endometriotic cells. Fertil Steril. 2008;90(1):234–237.

    Article  Google Scholar 

  19. Zhou M, Fu J, Xiao L, et al. miR-196a overexpression activates the MEK/ERK signal and represses the progesterone receptor and decidualization in eutopic endometrium from women with endometriosis. Hum Reprod. 2016. doi:10.1093/humrep/dew223.

    Google Scholar 

  20. Götte M, Kiesel L. Endocrine aspects of endometrial stem cell function in reproductive-age women. J Reproduktionsmed Endokrinol. 2013;10(Special Issue 1):120–125.

    Google Scholar 

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Authors and Affiliations

  1. Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood “G. Barresi,”, University of Messina, Messina, Italy

    Antonio Simone Laganà MD, Salvatore Giovanni Vitale MD & Onofrio Triolo MD

  2. Department of Biomedical Sciences, Dentistry and Morphological and Functional Imaging, University of Messina, Messina, Italy

    Francesca Maria Salmeri MD

  3. Department of Gynecology and Obstetrics, Münster University Hospital, Münster, Germany

    Martin Götte PhD

Authors
  1. Antonio Simone Laganà MD
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  2. Francesca Maria Salmeri MD
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  3. Salvatore Giovanni Vitale MD
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  4. Onofrio Triolo MD
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  5. Martin Götte PhD
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Corresponding author

Correspondence to Antonio Simone Laganà MD.

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Laganà, A.S., Salmeri, F.M., Vitale, S.G. et al. Stem Cell Trafficking During Endometriosis: May Epigenetics Play a Pivotal Role?. Reprod. Sci. 25, 978–979 (2018). https://doi.org/10.1177/1933719116687661

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  • DOI: https://doi.org/10.1177/1933719116687661

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