Abstract
Objectives
To systematically assess the outcomes and effectiveness of Prescription Automatic Screening System (PASS) on rational drug use in China.
Methods
All studies that evaluated the effects of PASS in Chinese hospitals were electronically searched. Meta-analysis was used to assess the outcomes of intervention effects.
Results
Twelve articles that appraised the interventions related to PASS were identified. All studies used before-after designs. Risk ratio was chosen as the effect size index. Heterogeneity was large (I2 > 50%) in all main analyses. Effect sizes were pooled using random effects. Compared with the control group, the pooled effect sizes were 0.60 (95% CI, 0.52-0.70) for the outcome of the incident of inpatient irrational drug use (n = 5), 0.75 (95% CI, 0.59-0.96) for the outcome of the incident of outpatient patient irrational drug use (n = 2), and 0.29 (95% CI, 0.10-0.86) for the outcome of the incidence of black-light warning orders (n = 6).
Conclusions
Interventions related to PASS was associated with the reduction of irrational drug use and medication errors.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Lijuan T, Peimin Y. Discussion on irrational drug use and counter measures in China Chin Pharm. 2005;16:1204–1206.
Black AD, Car J, Pagliari C, et al. The impact of eHealth on the quality and safety of health care: a systematic overview. PLoS Med. 2011;8:1–16.
Rahimi B, Timpka T, Vimarlund V, Uppugunduri S, Svensson M. Organization-wide adoption of computerized provider order entry systems: a study based on diffusion of innovations theory. BMC Med Inform Decis Mak. 2009;9:52.
Riedmann D, Jung M, Hackl WO, Stühlinger W, van der Sijs H, Ammenwerth E. Development of a context model to prioritize drug safety alerts in CPOE systems. BMC Med Inform Decis Mak. 2011;11:35.
Zhangwei Y, Jinhong H, Gongcheng S. The impact of clinical drug use decision-making system on rational drug use and the economic assessment methods. Chin Pharm. 2006;17:385–387.
Chaoyan L, Hai Z, Xiu L. Retrospective analysis of monitoring medication by using PASS. Guide Chin Med. 2009;7:34–35.
Qing X, Jin Y, Lixian G, et al. Comprehensive interventions to improve rational administration in medical orders for inpatients. Mil Med J S Chin. 2010;24:154–155.
Jin Y, Lixian G, Lei S, et al. Investigation and intervention study on monitoring medication by using PASS in our hospital. Guangdong Med J. 2006;27:1077–1078.
Xiuqin W, Qiuyu Q, Yanchun T, et al. Monitoring and analysis on medication orders for inpatients by using PASS. Chin J Drug Appl Monit. 2011;8:52–54.
Beijiang W, Fenfang W, Shiping H. Using clinical rational drug use monitor systems and improving the level of rational drug use. Nurs J Chin PLA. 2005;22:72–73.
Man Z, Daihong G, Guiyang L, et al. Evaluation of prescription automatic screening system in our hospital. Chin Pharm. 2010;19:41–42.
Bin Z, Maobo L, Xiaofang Z. Monitoring and analysis of hospital medication orders using PASS. Strait Pharm J. 2010;22:200–202.
Guiru L. Analysis on irrational drug use of outpatient prescription. Pharm Care Res. 2007;7:119–123.
Xiuyin X, Bo B, Guanghui H, et al. Development and application of prescription supervisory system for outpatient doctors work station. Chin J Pharmacovigilance. 2010;7:91–94.
Yan Z, Juying H, Peiyuan X. PASS system combining administrative intervention in promoting rational use of drugs in our hospital. Chin Pharm. 2008;19:2313–2314.
Renjie Z, Qin Z, Huiqing S, et al. Factors influencing clinical intervention of prescription automatic screening system. Pharm Care Res. 2004;4:197–200.
Jianli G, Xiaobo Z, Li S, et al. Intervention effect of Prescription Automatic Screening System in elderly patients. Chin J Mult Organ Dis Elderly. 2010;9:114–122.
Cochrane Effective Practice and Organization of Care Group: Data Abstraction form. 2011. https://doi.org/epoc.cochrane.org/epoc-resources-review-authors. Accessed September 18, 2011.
Perrier L, Mrklas K, Lavis JN, Straus SE. Interventions encouraging the use of systematic reviews by health policymakers and managers: a systematic review. Implement Sci. 2011;6:43.
Reckmann MH, Westbrook JI, Koh Y, Lo C, Day RO. Does computerized provider order entry reduce prescribing errors for hospital inpatients? A systematic review. J Am Med Inform Assoc. 2009;16:613–623.
Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions version 5.1.0. 2011. https://doi.org/www.cochrane-handbook.org/. Accessed September 18, 2011.
Pearson SA, Moxey A, Robertson J, et al. Do computerized clinical decision support systems for prescribing change practice? A systematic review of the literature (1990–2007). BMC Health Serv Res. 2009;9:154.
Chaudhry B, Wang J, Wu S, et al. Systematic review: impact of health information technology on quality, efficiency, and cost of medical care. Ann Int Med. 2006;144:12–22.
van der Sijs H, Aarts J, Vulto A, Berg M. Overriding of drug safety alerts in computerized physician order entry. J Am Med Inform Assoc. 2006;13:138–147.
Eslami S, de Keizer NF, Abu-Hanna A. The impact of computerized physician medication order entry in hospitalized patients—a systematic review. Int J Med Inform. 2008;77:365–376.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Yang, C., Yang, L., Xiang, X. et al. Interventions Assessment of Prescription Automatic Screening System in Chinese Hospitals: A Systematic Review. Ther Innov Regul Sci 46, 669–676 (2012). https://doi.org/10.1177/0092861512454417
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1177/0092861512454417