Figure S2 from CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy

Cao, Anthony; Yi, Jiaqing; Tang, Xinyan; Szeto, Christopher W.; Wu, Renyi; Wan, Bing; Fang, Xu; Li, Shou; Wang, Lei; Wang, Lina; Li, Jing; Ye, Qiuping; Huang, Tom; Hsu, Karl; Kabbarah, Omar; Zhou, Haiying

doi:10.1158/2767-9764.22545300.v1

crc-22-0266-s02.pdf (56.23 kB)

Figure S2 from CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy

journal contribution

posted on 2023-04-04, 01:42 authored by Anthony Cao, Jiaqing Yi, Xinyan Tang, Christopher W. Szeto, Renyi Wu, Bing Wan, Xu Fang, Shou Li, Lei Wang, Lina Wang, Jing Li, Qiuping Ye, Tom Huang, Karl Hsu, Omar Kabbarah, Haiying Zhou

CD47 expression and phagocytosis by ZL-1201

Funding

N/A

History

ARTICLE ABSTRACT

ZL-1201 is a novel anti-CD47 antibody that has improved hematologic safety profiles and combines with SoC, including mAbs and chemotherapies, to potently facilitate phagocytosis and antitumor efficacy.