Decision analysis and screening for Down's syndrome

Estimate of uptake of amniocentesis is overoptimistic

EDITOR,--J Fletcher and colleagues raise many important issues regarding the difficulties in making population policies for antenatal screening for Down's syndrome.1 Unlike in some previous studies, the authors give full attention to a wide range of outcome measures in their comparison of possible alternative policies rather than focusing simply on the number of cases of Down's syndrome detected. They also …