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Application of Nanotechnologies in Studying Yeast Structure in Candida

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Abstract

This review considers the methods of probe, electron, and confocal microscopy for studying the structure of the yeast Candida. The latest advances in the study of antimicrobial effects by high-resolution microscopy are presented. The advantages and disadvantages of each method are presented, as well as the limits of their application. Processes such as cell wall lysis and destruction of the cytoplasmic membrane caused by antifungal drugs are described, as well as their effect on the nanostructural or mechanical properties of Candida. Particular attention is paid to sample preparation of Candida and scanning protocols.

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Funding

The study was financed by the Russian Science Foundation (project no. 19-19-00626).

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  1. MISiS National University of Science and Technology, Moscow, Russia

    N. A. Savin, V. S. Kolmogorov, R. V. Timoshenko, Yu. N. Parkhomenko, S. V. Salikhov, A. G. Majouga, A. S. Erofeev & P. V. Gorelkin

  2. Moscow State University, Moscow, Russia

    N. L. Klyachko, A. G. Majouga & A. S. Erofeev

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  1. N. A. Savin
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Savin, N.A., Kolmogorov, V.S., Timoshenko, R.V. et al. Application of Nanotechnologies in Studying Yeast Structure in Candida. Nanotechnol Russia 16, 450–472 (2021). https://doi.org/10.1134/S263516762104011X

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