Skip to main content
SpringerLink
Log in

Synthesis of New Spiroindolinopyrrolidines

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

New substituted spiropyrrolidines were obtained by the 1,3-dipolar cycloaddition reaction of new dipolarophiles—3-phenyl-1-pyrrol-2-ylprop-2-en-1-ones—and azomethine ylides based on isatin and amino acids (sarcosine, proline) or benzylamine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Scheme
Scheme
Scheme
Scheme
Scheme
Scheme

Similar content being viewed by others

REFERENCES

  1. Pavlovska, T.L., Redkin, R.G., Lipson, V.V., and Atamanuk, D.V., Mol. Divers., 2016, vol. 20, p. 299. https://doi.org/10.1007/s11030-015-9629-8

    Article  CAS  PubMed  Google Scholar 

  2. Yu, B., Yu, D.-Q., and Liu, H.-M., Eur. J. Med. Chem., 2015, vol. 97, p. 637. https://doi.org/10.1016/j.ejmech.2014.06.056

    Article  CAS  Google Scholar 

  3. Santos, M., Tetrahedron, 2014, vol. 70, p. 9735. https://doi.org/10.1016/j.tet.2014.08.005

    Article  CAS  Google Scholar 

  4. Martina, K., Tagliapietra, S., Veselov, V.V., and Cravotto, G., Front. Chem., 2019, vol. 7, p. 95. https://doi.org/10.3389/fchem.2019.00095

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Bhardwaj, V., Gumber, D., Abbot, V., and Dhiman, S., RSC Adv., 2015, vol. 5, p. 15233. https://doi.org/10.1039/C4RA15710A

    Article  CAS  Google Scholar 

  6. Petri, G.L., Spanò, V., Spatola, R., Holl, R., Raimondi, M.V., Barraja, P., and Montalbano, A., Eur. J. Med. Chem., 2020, vol. 208, p. 112783. https://doi.org/10.1016/j.ejmech.2020.112783

    Article  CAS  Google Scholar 

  7. Iqbal, S., Rasheed, H., Awan, R.J., Awan, R.J., Mukhtar, A., Moloney, M.G., Curr. Org. Chem., 2020, vol. 24, p. 11657. https://doi.org/10.2174/1385272824999200528125651

    Article  CAS  Google Scholar 

  8. Estévez, V., Villacampa, M., and Menéndez, J.C., Chem. Soc. Rev., 2014, vol. 43, p. 4633. https://doi.org/10.1039/c3cs60015g

    Article  CAS  PubMed  Google Scholar 

  9. Tzankova, D., Vladimirova, S., Peikova, L., and Georgieva, M., J. Chem. Technol. Metallurgy, 2018, vol. 53, p. 3.

    Google Scholar 

  10. Adrio, J. and Carretero, C., Chem. Commun., 2019, vol. 55, p. 11979. https://doi.org/10.1039/C9CC05238K

    Article  CAS  Google Scholar 

  11. Singh, M.S., Chowdhury, S., and Koley, S., Tetrahedron, 2016, vol. 72, p. 1603. https://doi.org/10.1016/j.tet.2016.02.031

    Article  CAS  Google Scholar 

  12. Kuznetsov, M.L., Russ. Chem. Rev., 2006, vol. 75, no. 11, p. 935. https://doi.org/10.1070/RC2006v075n11ABEH001195

    Article  CAS  Google Scholar 

  13. Nájera, C. and Sansano, J.M., Curr. Org. Chem., 2003, vol. 7, p. 1105. https://doi.org/10.2174/1385272033486594

    Article  Google Scholar 

  14. Grigg, R., Aly, M.F., Sridharan, V., and Thianpatanagul, S.J., Chem. Soc. Commun., 1984, vol. 182, p. 10444. https://doi.org/10.1039/P19840000041

    Article  Google Scholar 

  15. Sarrafi, Y., Hamzehloueia, M., Alimohammadi, K., and Yeganegi, S., J. Mol. Struct., 2012, vol. 1030, p. 168. https://doi.org/10.1016/j.molstruc.2012.04.013

    Article  CAS  Google Scholar 

  16. Özdemir, A., Altıntop, M.D., Sever, B., Gençer, H.K., Kapkaç, H.A., Atlı, Ö., and Baysal, M., Molecules, 2017, vol. 22, p. 2112. https://doi.org/10.3390/molecules22122112-2128

    Article  PubMed Central  Google Scholar 

  17. Mohamed, A.A. and Radwaneman, M.H., Monatsh. Chem., 2009, vol. 140, p. 229. https://doi.org/10.1007/s00706-008-0061-y

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. N.G. Chernyshevsky Saratov National Research State University, 410012, Saratov, Russia

    S. V. Borisova & V. V. Sorokin

Authors
  1. S. V. Borisova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. V. Sorokin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. V. Borisova.

Ethics declarations

No conflict of interest was declared by the authors.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Borisova, S.V., Sorokin, V.V. Synthesis of New Spiroindolinopyrrolidines. Russ J Gen Chem 92, 10–17 (2022). https://doi.org/10.1134/S1070363222010030

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363222010030

Keywords:

Search

Navigation