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Theranostics for Oncological Therapy: The Results of World Research and Development Methods

  • MEDICAL BIOPHYSICS
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Abstract

Theranostics is a field of medicine where drugs are developed that are both therapeutic agents and tools for the early diagnosis of diseases. Their application is primarily associated with the targeted delivery of the agent to target cells. The development of a clinically effective theranostic drug will be the biggest breakthrough in medicine. This analytical mini-review describes modern approaches to solving problems of theranostics of oncological diseases. Recent studies on the use of radiopharmaceuticals and systems for the MRI imaging of cancerous tumors that are, at the same time, a therapeutic agent are described; information is given on the use of various systems based on fluorescent molecules, in particular, anti-Stokes fluorophores, whose signal is clearly distinguishable under the background fluorescence of tissues surrounding cancer cells, compared with other fluorescent substances. Information is also provided on the comparative use of classical chemotherapeutic agents and promising drugs based on natural substances with less toxicity, such as sulforaphane and cytochrome c.

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Authors and Affiliations

  1. State Scientific Center of the Russian Federation, Burnazyan Federal Medical Biophysical Center, Federal Medical Biological Agency of Russia, 123098, Moscow, Russia

    L. A. Romodin

  2. Russian Biotechnological University, 125080, Moscow, Russia

    L. A. Romodin

Authors
  1. L. A. Romodin
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Correspondence to L. A. Romodin.

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The author declares that he has no conflicts of interest.

This article does not contain any studies involving humans or animals as research subjects.

Additional information

Translated by E. Puchkov

Abbreviation: MRI, magnetic resonance imaging.

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Romodin, L.A. Theranostics for Oncological Therapy: The Results of World Research and Development Methods. BIOPHYSICS 68, 302–305 (2023). https://doi.org/10.1134/S0006350923020203

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  • DOI: https://doi.org/10.1134/S0006350923020203

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